{"id":"W2156001353","doi":"10.1038/ng.302","title":"Increased LIS1 expression affects human and mouse brain development","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Lissencephaly; Biology; Gene duplication; Gene; Genetics; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766237,0.0005479719,0.0003650532,0.001117039,0.0002852339,0.000522547,0.0003268079,0.0006421889,0.003320089],"category_scores_gemma":[0.0002822296,0.0004008772,0.0003846109,0.0004786197,0.0007081655,0.0002282837,0.0004670918,0.0006358684,0.0005042211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004251907,"about_ca_system_score_gemma":0.0003133568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001246796,"about_ca_topic_score_gemma":0.001518883,"domain_scores_codex":[0.9997476,0.00004095355,0.00003023786,0.00007813444,0.00006020695,0.00004281822],"domain_scores_gemma":[0.9997267,0.00007103375,0.0001091335,0.00002927092,0.00001586441,0.00004789381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003771596,0.00002116418,0.0009562813,0.0000436597,0.00002601268,0.0007993028,0.00003218067,0.000216764,0.9949255,0.0003218907,0.000115154,0.002165012],"study_design_scores_gemma":[0.00005425729,0.0002599846,0.0300207,0.0000161016,0.0001620507,0.006000734,0.00009084428,0.001234153,0.9571875,0.0004218945,0.004528687,0.00002314892],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924173,0.001302801,0.00246105,0.000218077,0.00004300682,0.00001488561,0.001042654,0.000247476,0.002252622],"genre_scores_gemma":[0.995388,0.0006300783,0.000968981,0.00007417388,0.00001323403,0.0000151408,0.0005780738,0.00009566491,0.002236643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003320089,"threshold_uncertainty_score":0.01110685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004633571051173868,"score_gpt":0.2304667833248371,"score_spread":0.2258332122736633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}