{"id":"W2156001353","doi":"10.1038/ng.302","title":"Increased LIS1 expression affects human and mouse brain development","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Lissencephaly; Biology; Gene duplication; Gene; Genetics; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008939712,0.0001350383,0.00009138967,0.0000320167,0.0001476597,0.00003327476,0.0001131285,0.0003036368,0.00001101532],"category_scores_gemma":[0.00002558597,0.0001252432,0.00002693729,0.00003637181,0.00002270347,0.000002191294,0.00006982514,0.0001344155,0.000002125108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001083722,"about_ca_system_score_gemma":0.00004777549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001507632,"about_ca_topic_score_gemma":0.00001209054,"domain_scores_codex":[0.9993401,0.00003305939,0.0001157172,0.0002397947,0.00009827269,0.0001730582],"domain_scores_gemma":[0.9996129,0.000005831026,0.00004725566,0.0002113035,0.00004126484,0.00008146132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001565785,0.00004332164,0.003204932,0.00001056622,0.00001216519,0.000001922405,0.0001290608,0.00001278249,0.9910961,0.00009998987,0.003682132,0.001691327],"study_design_scores_gemma":[0.0004134209,0.0001784967,0.04562852,0.00001008409,0.000005953619,0.00001085952,0.00004024821,0.000005456763,0.9044892,0.000100474,0.04893347,0.0001837963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997031,0.001814615,0.0001258678,0.0001420173,0.00004906874,0.0001160255,0.000008958916,0.00001446177,0.0006979431],"genre_scores_gemma":[0.9927787,0.00006330392,0.004884976,0.0009389193,0.0001926531,0.000005585299,0.0001683795,0.00001182513,0.0009557187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08660692,"threshold_uncertainty_score":0.5107267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004633571051173868,"score_gpt":0.2304667833248371,"score_spread":0.2258332122736633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}