{"id":"W2156016194","doi":"10.1371/journal.pone.0014827","title":"Characterization of 14-3-3 Proteins from Cryptosporidium parvum","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Structural Genomics Consortium","funders":"Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada; Ontario Innovation Trust; Wellcome Trust; Ontario Genomics Institute; Wellcome; GlaxoSmithKline","keywords":"Protein subunit; Peptide; Footprinting; Cryptosporidium parvum; Phosphopeptide; Dimer; Binding site; Plasma protein binding; Computational biology; Peptide sequence; Protein–protein interaction; Chemistry; Biology; Crystallography; Biochemistry; DNA; Genetics; Base sequence; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001956971,0.0005694833,0.0002453926,0.0004303015,0.0002642109,0.0003208496,0.0003541457,0.0005382003,0.001689871],"category_scores_gemma":[0.0003780338,0.000140994,0.0003515872,0.0006060661,0.0001749554,0.0002111003,0.0002617917,0.0004923714,0.001219059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000359903,"about_ca_system_score_gemma":0.0002931234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001538412,"about_ca_topic_score_gemma":0.00164778,"domain_scores_codex":[0.9998595,0.000008492248,0.00001057416,0.00004031945,0.00005532368,0.00002583665],"domain_scores_gemma":[0.9997861,0.0000401394,0.00004229381,0.00001826812,0.00006045219,0.00005277171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001533802,0.00004207543,0.001942989,0.0001276345,0.000009432208,0.0001570804,0.0000388966,0.00008700282,0.9932417,0.00005627517,0.0002201907,0.00392346],"study_design_scores_gemma":[0.00005315643,0.0004265266,0.127386,0.00007206648,0.0001069919,0.003303732,0.0001795995,0.003516657,0.8284541,0.0002710299,0.0362036,0.00002657361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802183,0.001875972,0.008301319,0.0002880205,0.00006936365,0.0001358865,0.006473933,0.0001863071,0.002450824],"genre_scores_gemma":[0.9175302,0.001458819,0.03807099,0.0003252881,0.00005826694,0.0002102824,0.03560285,0.0002467517,0.006496469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001689871,"threshold_uncertainty_score":0.005653203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03928732205464536,"score_gpt":0.2100253292630982,"score_spread":0.1707380072084528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}