{"id":"W2156038908","doi":"10.4049/jimmunol.1300096","title":"Macrophages Are More Potent Immune Suppressors Ex Vivo Than Immature Myeloid-Derived Suppressor Cells Induced by Metastatic Murine Mammary Carcinomas","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"BC Cancer Agency; BC Cancer Foundation; Canadian Institutes of Health Research; Terry Fox Foundation; Michael Smith Health Research BC","keywords":"Immune system; Myeloid-derived Suppressor Cell; Cancer research; Myeloid; Biology; Ex vivo; Immunology; T cell; Metastatic breast cancer; Myelopoiesis; Haematopoiesis; In vivo; Cancer; Stem cell; Suppressor; Cell biology; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003306305,0.000441871,0.0004763322,0.0004333695,0.0001371968,0.0002777906,0.000130168,0.0003226533,0.001200014],"category_scores_gemma":[0.0002041074,0.0001872594,0.0002657223,0.0001086606,0.000188372,0.0001930843,0.0002502357,0.000884097,0.0004649635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720514,"about_ca_system_score_gemma":0.0001572385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002183376,"about_ca_topic_score_gemma":0.0002599588,"domain_scores_codex":[0.9996529,0.00007614129,0.00003529981,0.00005173276,0.0000841495,0.00009985855],"domain_scores_gemma":[0.9996688,0.00006810747,0.00006830045,0.00005399024,0.00003919865,0.0001015929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001144906,0.00003753096,0.0002051803,0.000009993258,0.000002096619,0.00003106937,0.00001256942,0.00002444577,0.9990349,0.00005170256,0.00001275237,0.0004633814],"study_design_scores_gemma":[0.00002863827,0.0008671433,0.003918451,0.000003208443,0.00001298364,0.000273479,0.00002211034,0.000416148,0.9930152,0.00004244374,0.001397014,0.000003139761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962748,0.001054363,0.001369582,0.00005466126,0.00001797154,0.00002818683,0.0001976009,0.00007838874,0.0009244559],"genre_scores_gemma":[0.9944464,0.0005146551,0.001480125,0.00004887328,0.00002778018,0.00006205471,0.0004143097,0.00003489982,0.002971011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001200014,"threshold_uncertainty_score":0.004014492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009203713626969838,"score_gpt":0.2197394995380049,"score_spread":0.2105357859110351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}