{"id":"W2156106990","doi":"10.1016/s0300-483x(03)00160-4","title":"Modulation of d-penicillamine-induced autoimmunity in the Brown Norway rat using pharmacological agents that interfere with arachidonic acid metabolism or synthesis of inducible nitric oxide synthase","year":2003,"lang":"en","type":"article","venue":"Toxicology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Penicillamine; Autoimmunity; Pharmacology; Nitric oxide; Nitric oxide synthase; Cyclooxygenase; Chemistry; Prostaglandin E; Misoprostol; Endocrinology; Internal medicine; Medicine; Immunology; Immune system; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001199095,0.0002466234,0.0008130174,0.0003443788,0.0000751894,0.000006314033,0.0002098342,0.0002633276,0.0004212785],"category_scores_gemma":[0.00091776,0.0001430597,0.000100721,0.0005965769,0.0001708886,0.0001047039,0.00003881109,0.0004689156,0.000006861728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001183459,"about_ca_system_score_gemma":0.0003008175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006344272,"about_ca_topic_score_gemma":0.00003525963,"domain_scores_codex":[0.9974341,0.001130196,0.0005009845,0.0002730492,0.0002959576,0.000365756],"domain_scores_gemma":[0.9983176,0.0007582008,0.0003548916,0.00039342,0.00009560666,0.0000802569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001536109,0.0006008578,0.01486776,0.0001533766,0.0001471834,0.000214121,0.0003471272,0.0002400321,0.9807134,0.0001293165,0.00002509578,0.00102564],"study_design_scores_gemma":[0.002498514,0.0005489155,0.1889101,0.0001194942,0.0004397364,0.0002462777,0.0003970592,0.001201986,0.8053903,0.00001607384,0.00007345458,0.0001580731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981565,0.0001343373,0.00007381063,0.0000911816,0.0001734448,0.0008922988,0.000004577917,0.00001695994,0.0004568602],"genre_scores_gemma":[0.9993589,0.00002947458,0.0002768112,0.000182977,0.00004145273,0.000051877,0.000003631925,0.00002284463,0.000032015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1753231,"threshold_uncertainty_score":0.5833807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07218110585048798,"score_gpt":0.32229144469087,"score_spread":0.250110338840382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}