{"id":"W2156122297","doi":"10.7717/peerj.558","title":"Protein kinase C in the wood frog, <i>Rana sylvatica</i> : reassessing the tissue-specific regulation of PKC isozymes during freezing","year":2014,"lang":"en","type":"article","venue":"PeerJ","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Protein kinase C; Phosphorylation; Isozyme; Biology; Protein phosphorylation; Kinase; Rana; Second messenger system; Cell biology; Biochemistry; Protein kinase A; Signal transduction; Enzyme; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007885548,0.0001160402,0.00017299,0.0000807734,0.0003418814,0.00004017609,0.0005400809,0.00007223379,0.00004118913],"category_scores_gemma":[0.0007828103,0.00006892205,0.00004275988,0.0003855,0.0003802068,0.0001511605,0.00009779424,0.0004076228,0.00002474494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001336112,"about_ca_system_score_gemma":0.00002031052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003091624,"about_ca_topic_score_gemma":0.00001441823,"domain_scores_codex":[0.9978386,0.00105913,0.0002532223,0.0003222594,0.0002242708,0.0003025589],"domain_scores_gemma":[0.9985048,0.000797161,0.0001125689,0.000527589,0.00003480435,0.00002308819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004831326,0.00005210176,0.0003927204,0.00002458859,0.000001357754,0.000004005898,0.0004979687,0.00003693302,0.9923078,0.005329071,0.00009560784,0.001209547],"study_design_scores_gemma":[0.0002939668,0.00008491307,0.05869397,0.00005504967,0.000003023782,0.00001421181,0.00009055646,0.0003392699,0.9356242,0.004103092,0.0006166546,0.00008101999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955914,0.00008068483,0.0000698455,0.001812078,0.00007549185,0.0004180262,0.000002849249,0.00002761823,0.001921991],"genre_scores_gemma":[0.999348,0.00001380745,0.0000450782,0.0002215604,0.0001011179,0.00004882419,0.000001968871,0.00001189777,0.0002077565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05830125,"threshold_uncertainty_score":0.281056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03541049211033157,"score_gpt":0.2861289640539218,"score_spread":0.2507184719435902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}