{"id":"W2156130318","doi":"10.1186/ar2031","title":"Preventing autoimmune arthritis using antigen-specific immature dendritic cells: a novel tolerogenic vaccine","year":2006,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University Health Network; Robarts Clinical Trials; Lawson Health Research Institute; London Health Sciences Centre","funders":"Canadian Institutes of Health Research; Lawson Health Research Institute","keywords":"Medicine; Rheumatology; Immunology; Arthritis; Antigen; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00200683,0.0005366054,0.000796011,0.0006419121,0.00168127,0.0002685188,0.0008331283,0.0005727478,0.002572723],"category_scores_gemma":[0.0000578898,0.0005395116,0.0004253728,0.001009845,0.0005635491,0.0004796353,0.0002127274,0.001494832,0.0007334999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001507757,"about_ca_system_score_gemma":0.0002732132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009933632,"about_ca_topic_score_gemma":0.0001262422,"domain_scores_codex":[0.9943727,0.001373712,0.001040538,0.0008951199,0.0003288399,0.001989087],"domain_scores_gemma":[0.9976698,0.0005427431,0.0002140562,0.001064244,0.0004533318,0.00005582367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001339908,0.0006721374,0.0001820218,0.000009231954,0.0002276199,0.00006947896,0.0003773473,0.00002605131,0.8785791,0.0005446038,0.002596666,0.1153758],"study_design_scores_gemma":[0.007931096,0.0005443009,0.006666342,0.0005317706,0.000003307563,0.0007298191,0.000357805,0.00002597102,0.5734754,0.0003923027,0.4087758,0.0005660486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6236419,0.3740221,0.0002914505,0.0002063346,0.0006800176,0.0007319907,0.00004873618,0.000154061,0.0002233443],"genre_scores_gemma":[0.8586169,0.1376739,0.0006913256,0.0001067869,0.0002155314,0.0001097402,0.0001424266,0.0001302413,0.002313143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4061792,"threshold_uncertainty_score":0.9997056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03677934897590626,"score_gpt":0.3013689647389559,"score_spread":0.2645896157630496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}