{"id":"W2156135830","doi":"10.1093/brain/awp319","title":"Integrin activation or alpha9 expression allows retinal pigmented epithelial cell adhesion on Bruch’s membrane in wet age-related macular degeneration","year":2010,"lang":"en","type":"article","venue":"Brain","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"John and Lucille Van Geest Foundation; European Commission","keywords":"Bruch's membrane; Macular degeneration; Retinal pigment epithelium; Integrin; Cell biology; Retinal; Focal adhesion; Cell adhesion; Adhesion; Chemistry; Biology; Cell; Medicine; Signal transduction; Ophthalmology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017938,0.0001739893,0.0001742541,0.0001489146,0.0001749963,0.0001947697,0.0001327098,0.0002845996,0.001021123],"category_scores_gemma":[0.0001625342,0.0001592379,0.0002159208,0.0001164534,0.0001757,0.0001589468,0.0001287042,0.0003638649,0.0002323656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002085315,"about_ca_system_score_gemma":0.0001027256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007521195,"about_ca_topic_score_gemma":0.0008741223,"domain_scores_codex":[0.9997925,0.00005235917,0.00003135853,0.00002836632,0.00004446616,0.00005102598],"domain_scores_gemma":[0.9999136,0.00002199233,0.00002074099,0.00001779266,0.000007599366,0.00001830264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005703144,0.00001871881,0.00008620874,0.00000879991,0.000001733488,0.00004715109,0.00001361071,0.00001049984,0.9995242,0.00003519457,0.00000849922,0.000188267],"study_design_scores_gemma":[0.00001918983,0.0003826291,0.008183978,0.000003721915,0.00001442924,0.0003597279,0.00004772441,0.0004976544,0.9892436,0.00003962576,0.001203705,0.000003944698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985512,0.000398033,0.0005470283,0.00003299741,0.00001134701,0.000007117023,0.00003821248,0.00001015958,0.0004040072],"genre_scores_gemma":[0.9971828,0.0003607716,0.0008203826,0.00002756729,0.000004927473,0.00001577288,0.0001418686,0.000006565087,0.001439308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001021123,"threshold_uncertainty_score":0.003416002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01943647334446507,"score_gpt":0.2969937840656453,"score_spread":0.2775573107211802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}