{"id":"W2156142989","doi":"10.1128/jvi.75.6.3028-3033.2001","title":"Simian Immunodeficiency Virus (SIV) Infection of a Rhesus Macaque Induces SIV-Specific CD8<sup>+</sup>T Cells with a Defect in Effector Function That Is Reversible on Extended Interleukin-2 Incubation","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institutes of Health; University of Toronto; National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network; Emory University","keywords":"Biology; Simian immunodeficiency virus; Cytotoxic T cell; Antigen; Virology; CD8; Epitope; Immunology; Molecular biology; Virus; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004996176,0.0002416722,0.000520137,0.0008676468,0.0001126612,0.00001491979,0.0001744666,0.0003493032,0.0006186953],"category_scores_gemma":[0.00006334776,0.0001783388,0.0001981067,0.0003903618,0.0002512303,0.0002265341,0.00004245641,0.0007739249,0.0002962386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002969273,"about_ca_system_score_gemma":0.0001155739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000312341,"about_ca_topic_score_gemma":0.0001622387,"domain_scores_codex":[0.9979507,0.0006885302,0.000530062,0.0002784798,0.0001292684,0.0004229164],"domain_scores_gemma":[0.9987114,0.0003451741,0.0005099063,0.0002392115,0.0001499699,0.00004434247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01592817,0.001724476,0.03221617,0.00004512325,0.0006978242,0.0001833532,0.001719997,0.001255716,0.9311662,0.00005468015,0.001087831,0.01392049],"study_design_scores_gemma":[0.02141107,0.05399694,0.2713086,0.0004975482,0.0004128325,0.002044384,0.001036088,0.00008312496,0.6355031,0.0005695467,0.01252664,0.0006101255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967237,0.001474035,0.0004965998,0.0001840305,0.0003093859,0.0003321618,0.00002038264,0.00001350004,0.000446168],"genre_scores_gemma":[0.9981368,0.0014965,0.00003116655,0.0001115877,0.00003714771,0.00001675614,0.00002940355,0.00001817534,0.0001224437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2956631,"threshold_uncertainty_score":0.7272443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01714070724974513,"score_gpt":0.2503326852574111,"score_spread":0.233191978007666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}