{"id":"W2156186195","doi":"10.1074/jbc.m503672200","title":"Huntingtin Associates with Acidic Phospholipids at the Plasma Membrane","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Huntingtin; Polyglutamine tract; Membrane; Huntingtin Protein; Chemistry; Biophysics; Biochemistry; Cell biology; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002280742,0.00016157,0.0002193594,0.00001116025,0.0001671848,0.00004490477,0.0004302359,0.00008452527,0.0006909089],"category_scores_gemma":[0.001386612,0.0000771957,0.0001344808,0.0001491285,0.0004056259,0.00004972409,0.0001068091,0.000309473,0.00003105303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006473981,"about_ca_system_score_gemma":0.00005250964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":5.179453e-7,"about_ca_topic_score_gemma":8.69077e-7,"domain_scores_codex":[0.9987349,0.0001042818,0.0003219883,0.0002275786,0.0003487367,0.0002625285],"domain_scores_gemma":[0.998751,0.0004569766,0.0004164604,0.0001593086,0.00008431515,0.000131898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001377946,0.0001008915,0.004354245,0.000005188204,0.000008600077,0.00002131085,0.00002160515,0.000193659,0.9940416,0.000004669366,0.0006515944,0.0004588646],"study_design_scores_gemma":[0.0004791122,0.0001228353,0.002384899,0.00001372873,0.00001784993,0.0002418487,0.00004506905,0.00002596326,0.9921084,0.00001590226,0.004434686,0.0001097193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960093,0.0001706568,0.000003932676,0.001993186,0.00005496015,0.00005043558,0.00001352091,0.00001620472,0.001687825],"genre_scores_gemma":[0.997475,0.0001273766,0.0001236497,0.0009306286,0.0003984174,0.000003220789,0.000001050027,0.000009522886,0.0009311867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003783092,"threshold_uncertainty_score":0.7564968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266051167478323,"score_gpt":0.248513882603368,"score_spread":0.2219087658555357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}