{"id":"W2156219379","doi":"10.1111/epi.12692","title":"<scp>WONOEP</scp> appraisal: New genetic approaches to study epilepsy","year":2014,"lang":"en","type":"review","venue":"Epilepsia","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; FP7 People: Marie-Curie Actions; Savoy Foundation; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Epileptogenesis; Epilepsy; Neuroscience; Biology; Optogenetics; Epigenetics; Cell type; Reprogramming; Dravet syndrome; Computational biology; Genetics; Gene; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001335376,0.0008089688,0.0007145229,0.001322803,0.001364112,0.003234741,0.001944093,0.004609795,0.169128],"category_scores_gemma":[0.004322032,0.0002516609,0.0007739751,0.001029623,0.001281007,0.001122578,0.001399418,0.003205694,0.05738825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003962345,"about_ca_system_score_gemma":0.004502063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01668538,"about_ca_topic_score_gemma":0.06604362,"domain_scores_codex":[0.9985963,0.0001211348,0.00007446251,0.0001143506,0.00089345,0.0002003588],"domain_scores_gemma":[0.9927601,0.0006453724,0.0002174824,0.0002868293,0.004633654,0.001456648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002396179,0.000004245041,0.00004336339,0.0001062821,0.000003106876,0.00007444147,0.00000498296,0.0000188368,0.0002199173,0.0003999317,0.9839273,0.01517365],"study_design_scores_gemma":[0.00001743406,0.00001797849,0.0007606713,0.0001855417,0.000005249377,0.0001820266,0.00002252191,0.00007462247,0.0002992127,0.0008285865,0.9975988,0.000007358859],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.001740546,0.02813137,0.00299779,0.2610752,0.222445,0.001092785,0.006111655,0.002446466,0.4739592],"genre_scores_gemma":[0.01086626,0.01768017,0.002412285,0.09053161,0.07960846,0.0005699496,0.004075926,0.000933074,0.7933222],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.169128,"threshold_uncertainty_score":0.5657895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08225068606399984,"score_gpt":0.3089128592829455,"score_spread":0.2266621732189457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}