{"id":"W2156268636","doi":"10.1055/s-0034-1398742","title":"Optimizing Antimicrobial Therapy of Sepsis and Septic Shock: Focus on Antibiotic Combination Therapy","year":2015,"lang":"en","type":"review","venue":"Seminars in Respiratory and Critical Care Medicine","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Septic shock; Intensive care medicine; Bacteremia; Sepsis; Antimicrobial; Endocarditis; Combination therapy; Antibiotics; Immunology; Internal medicine; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001271297,0.0008810007,0.002567574,0.002811226,0.0002497511,0.001157355,0.0009046686,0.001183994,0.002798156],"category_scores_gemma":[0.002585568,0.0003008801,0.001610383,0.003063223,0.0005423113,0.00145216,0.0006708685,0.001906026,0.0007020098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008169432,"about_ca_system_score_gemma":0.001636256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001298589,"about_ca_topic_score_gemma":0.002299306,"domain_scores_codex":[0.9992782,0.0002289821,0.0001521369,0.00009074042,0.0002120453,0.0000378745],"domain_scores_gemma":[0.9984307,0.001130076,0.0001819199,0.00002781572,0.0001901465,0.00003936316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001376311,0.00009178196,0.0003120466,0.125946,0.0007852815,0.0001354336,0.00008524195,0.0003636657,0.0006016772,0.002370073,0.01969262,0.8494787],"study_design_scores_gemma":[0.0001531967,0.0003688358,0.003826427,0.1272987,0.003360871,0.002801491,0.0002307649,0.0003039649,0.0005999016,0.00410426,0.8568968,0.00005485236],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003963838,0.9995909,0.0000278292,0.0001399961,0.0000482443,0.000002037312,0.000004514168,0.000001445418,0.0001453258],"genre_scores_gemma":[0.0003984183,0.9992775,0.0000938565,0.0001121168,0.00005940538,0.000003509337,0.000006601674,6.057023e-7,0.00004810711],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002811226,"threshold_uncertainty_score":0.00936079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1346280146883309,"score_gpt":0.4201900730930945,"score_spread":0.2855620584047637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}