{"id":"W2156437245","doi":"10.1124/mol.60.1.92","title":"Dopamine D<sub>4</sub>and D<sub>2L</sub>Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on<i>trans-</i>Activation of the Platelet-Derived Growth Factor Receptor","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Platelet-derived growth factor receptor; Wortmannin; Autophosphorylation; Biology; Tyrosine kinase; Chemistry; Receptor; Cell biology; Molecular biology; Protein kinase A; Signal transduction; Kinase; Biochemistry; Protein kinase B; Growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002042106,0.0003667319,0.0003453326,0.00008688034,0.0001723059,0.00001658708,0.0003545346,0.000343031,0.0001404793],"category_scores_gemma":[0.00008670724,0.0002742294,0.0002407165,0.0002875751,0.0001710441,0.00001612562,0.0001543943,0.0002909655,0.000003561252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005554067,"about_ca_system_score_gemma":0.0001259475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002072563,"about_ca_topic_score_gemma":0.000003995413,"domain_scores_codex":[0.9977166,0.0004580926,0.0005105148,0.000563033,0.0003755127,0.0003762588],"domain_scores_gemma":[0.9987631,0.00003996802,0.000448935,0.0003727973,0.000267411,0.0001077424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007384342,0.0002033729,0.0001282094,0.00005459799,0.0002062889,0.000002905006,0.0001553713,0.0003648057,0.9943715,0.00002944887,0.0001137555,0.003631344],"study_design_scores_gemma":[0.002010952,0.0004440119,0.0003874769,0.00005341569,0.00004466999,0.000007362779,0.00002715397,0.0001434147,0.9955308,0.00004764709,0.001017367,0.0002856939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938639,0.0001867957,0.003509014,0.0004004508,0.000558658,0.001340758,0.0001013006,0.00001754637,0.00002156875],"genre_scores_gemma":[0.9988193,0.0001719626,0.00009239383,0.0005243763,0.0001302161,0.0001039339,0.0000729819,0.00006149089,0.00002336723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00495537,"threshold_uncertainty_score":0.999971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00963308136360346,"score_gpt":0.2266476989535418,"score_spread":0.2170146175899383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}