{"id":"W2156437245","doi":"10.1124/mol.60.1.92","title":"Dopamine D<sub>4</sub>and D<sub>2L</sub>Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on<i>trans-</i>Activation of the Platelet-Derived Growth Factor Receptor","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Platelet-derived growth factor receptor; Wortmannin; Autophosphorylation; Biology; Tyrosine kinase; Chemistry; Receptor; Cell biology; Molecular biology; Protein kinase A; Signal transduction; Kinase; Biochemistry; Protein kinase B; Growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007870523,0.0004673497,0.0002452079,0.0002845302,0.000271451,0.0005134803,0.0002123001,0.0002540169,0.002675428],"category_scores_gemma":[0.000162505,0.0002490914,0.0004660951,0.0001463067,0.000312702,0.0003105782,0.0002765357,0.0006914522,0.0009992456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001051353,"about_ca_system_score_gemma":0.0004509184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00171784,"about_ca_topic_score_gemma":0.003748917,"domain_scores_codex":[0.9998664,0.00002351396,0.000007691377,0.00001462668,0.00002529157,0.00006242472],"domain_scores_gemma":[0.9999187,0.00001091817,0.00003128574,0.000009539955,0.000007835642,0.00002171585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001115101,0.00009205937,0.0004464332,0.00006661636,0.00002658379,0.0002463705,0.00003853372,0.0001640525,0.9911027,0.001770724,0.0002504219,0.00468042],"study_design_scores_gemma":[0.0001344532,0.0005890456,0.01859343,0.00002072329,0.00002933569,0.001043895,0.0001760605,0.001293919,0.9714347,0.0009187158,0.005742677,0.00002315083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838011,0.004477483,0.002109946,0.0004230268,0.0000747345,0.00004267248,0.0008064639,0.000111005,0.008153674],"genre_scores_gemma":[0.9872702,0.002492008,0.001902255,0.0001296784,0.00001803429,0.00008120519,0.001066315,0.00003242422,0.007007927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002675428,"threshold_uncertainty_score":0.008950174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00963308136360346,"score_gpt":0.2266476989535418,"score_spread":0.2170146175899383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}