{"id":"W2156456343","doi":"10.1093/hmg/ddh008","title":"Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis","year":2003,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":336,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Toyobo Biotechnology Foundation; Crohn's and Colitis Foundation; Johns Hopkins University; Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation of America","keywords":"Biology; Genetics; Allele; Linkage disequilibrium; Single-nucleotide polymorphism; Haplotype; Molecular biology; Inflammatory bowel disease; Gene; Genotype; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219184,0.0002696182,0.0002019104,0.0004351122,0.0002107442,0.0001792499,0.0002171505,0.0003025367,0.00224197],"category_scores_gemma":[0.0004681788,0.00009831639,0.0003237395,0.0003574994,0.00009792444,0.00003751662,0.0001150995,0.0002477617,0.0004737046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001614334,"about_ca_system_score_gemma":0.0001308572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001879205,"about_ca_topic_score_gemma":0.001794088,"domain_scores_codex":[0.9998914,0.00002722244,0.000009359875,0.00003677044,0.00002264728,0.00001248313],"domain_scores_gemma":[0.9997151,0.00009098282,0.00009612239,0.00001806045,0.0000282092,0.00005131713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004051533,0.0004118662,0.2150497,0.0004848265,0.0003404752,0.007514224,0.0005207813,0.001140128,0.7158167,0.0004941165,0.002015532,0.05216007],"study_design_scores_gemma":[0.0003313035,0.0005116877,0.9296137,0.0001180535,0.000413713,0.01690907,0.0001703444,0.00428643,0.03729159,0.0004328354,0.009882006,0.00003934115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956732,0.000764289,0.001267164,0.0001317524,0.00002950775,0.00001542481,0.001321159,0.00005124367,0.0007461149],"genre_scores_gemma":[0.9951221,0.0001918781,0.001875465,0.00008727359,0.00003013268,0.00001510125,0.001816764,0.0000202078,0.0008410206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00224197,"threshold_uncertainty_score":0.007500112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01914778312761051,"score_gpt":0.2517053978640504,"score_spread":0.2325576147364399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}