{"id":"W2156456343","doi":"10.1093/hmg/ddh008","title":"Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis","year":2003,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":336,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Toyobo Biotechnology Foundation; Crohn's and Colitis Foundation; Johns Hopkins University; Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation of America","keywords":"Biology; Genetics; Allele; Linkage disequilibrium; Single-nucleotide polymorphism; Haplotype; Molecular biology; Inflammatory bowel disease; Gene; Genotype; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001824083,0.000209192,0.0001491323,0.00006456154,0.0001420143,0.00002375488,0.0001135735,0.0001466578,0.00005169775],"category_scores_gemma":[0.0001406863,0.0002329788,0.0001729307,0.00005238702,0.0001347874,0.000004372521,0.00004069106,0.00006187423,0.000003189338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001971364,"about_ca_system_score_gemma":0.0001520502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001147567,"about_ca_topic_score_gemma":0.00004609524,"domain_scores_codex":[0.9987733,0.0001375462,0.0002634046,0.0003702108,0.0002064198,0.000249169],"domain_scores_gemma":[0.9990208,0.00001294602,0.0002083015,0.0003738334,0.0002747197,0.000109472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004063041,0.000432952,0.009249584,0.0000737604,0.0002467202,0.00001878075,0.0001009726,0.0009668167,0.9815236,0.005802112,0.0009146901,0.0002637104],"study_design_scores_gemma":[0.003418128,0.0004563532,0.4252932,0.00002309239,0.0001859035,0.00002277526,0.00007677403,0.000255351,0.5657926,0.001529054,0.002492146,0.0004546563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9429358,0.0002616894,0.05535412,0.000008497756,0.00007366146,0.0006265496,0.0002947501,0.00001067671,0.000434275],"genre_scores_gemma":[0.9933082,0.00002199221,0.00554664,0.000160314,0.0000874703,0.0001311444,0.0004731959,0.00004882421,0.0002222511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4160436,"threshold_uncertainty_score":0.9500601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01914778312761051,"score_gpt":0.2517053978640504,"score_spread":0.2325576147364399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}