{"id":"W2156460145","doi":"10.1161/01.atv.0000147162.51930.b7","title":"Granzyme B Induces Smooth Muscle Cell Apoptosis in the Absence of Perforin","year":2004,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia","funders":"","keywords":"Granzyme B; Granzyme; Perforin; Cell biology; Granzyme A; Biology; Programmed cell death; Apoptosis; Extracellular; Molecular biology; Chemistry; Cytotoxic T cell; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003354191,0.0001636542,0.0002201662,0.00005667903,0.0000994513,0.00001843751,0.0001978278,0.0001920984,0.00001192788],"category_scores_gemma":[0.0000102655,0.000115662,0.0001239988,0.0001310056,0.0001587964,0.000007322602,0.00007969295,0.00007932688,0.000002260926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007983066,"about_ca_system_score_gemma":0.00002266123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002061499,"about_ca_topic_score_gemma":0.0000889108,"domain_scores_codex":[0.9989771,0.0001021071,0.0002527095,0.0003494794,0.00008897763,0.0002296056],"domain_scores_gemma":[0.9994833,0.00001317559,0.00009292091,0.0003387669,0.00003366762,0.00003819594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00000177984,0.0001236585,0.007266505,0.00001791602,0.0000184534,1.21187e-8,0.0003465015,0.00003306421,0.9910331,0.0005767681,0.00001155387,0.0005707039],"study_design_scores_gemma":[0.0008880256,0.0004894112,0.9222063,0.00002800125,0.00002239573,2.447768e-7,0.000385318,0.00001190242,0.07352838,0.0003372277,0.001918241,0.0001844877],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985583,0.0002166937,0.0005545327,0.0002296815,0.00009770944,0.0002064265,0.000008249523,0.0000053773,0.0001230411],"genre_scores_gemma":[0.9952781,0.003929572,0.000445956,0.0001946374,0.00006047493,0.00003139004,0.00004500611,0.00001291572,0.000001983843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9175047,"threshold_uncertainty_score":0.4716558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02035570393197506,"score_gpt":0.248595520581132,"score_spread":0.228239816649157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}