{"id":"W2156498191","doi":"10.1002/pbc.21737","title":"Outcome and toxicity of chemotherapy for acute lymphoblastic leukemia in children with down syndrome","year":2008,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Mucositis; Adverse effect; Methotrexate; Chemotherapy; Toxicity; Incidence (geometry); Acute lymphocytic leukemia; Pediatrics; Internal medicine; Leukemia; Lymphoblastic Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001589192,0.0002727303,0.0007228342,0.0003151609,0.0000683594,0.000007851478,0.0001637167,0.000163972,0.0000759672],"category_scores_gemma":[0.00007057617,0.0002094309,0.0000880556,0.0006506773,0.0001944012,0.00009563712,0.00005707283,0.0002048031,0.000003557058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006805848,"about_ca_system_score_gemma":0.002024944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006398664,"about_ca_topic_score_gemma":0.00003783992,"domain_scores_codex":[0.9980201,0.0000219646,0.0004642854,0.0004722083,0.0004919601,0.0005294789],"domain_scores_gemma":[0.9989824,0.0001807102,0.0001559184,0.0003169475,0.000139011,0.0002249568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007534686,0.0001701947,0.9966767,0.0002389821,0.0004679368,0.0001001973,0.0001709434,0.00004439355,0.00067768,0.000007827451,0.0004002117,0.000291463],"study_design_scores_gemma":[0.02384662,0.001271203,0.967638,0.00006091149,0.001204388,0.002672347,0.00001045498,0.0004858771,0.002474344,0.00001554145,0.00002839331,0.0002919055],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969117,0.001223573,0.0002517175,0.000188011,0.00004375953,0.001148779,0.0001158565,0.00004153317,0.00007505726],"genre_scores_gemma":[0.9939767,0.003194348,0.001557987,0.0003264286,0.0002878905,0.000230392,0.00001555296,0.0000603635,0.0003503508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02903869,"threshold_uncertainty_score":0.8540347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01204884026677019,"score_gpt":0.2810177449806092,"score_spread":0.268968904713839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}