{"id":"W2156567043","doi":"10.1093/carcin/bgv028","title":"Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression","year":2015,"lang":"en","type":"review","venue":"Carcinogenesis","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Western University; Health Canada; Dalhousie University","funders":"National Institute of Environmental Health Sciences; National Cancer Institute","keywords":"Evasion (ethics); Cancer; Growth inhibition; Cancer cell; Biology; Retinoblastoma; Retinoblastoma protein; Growth factor; Cell growth; Cell biology; Cancer research; Immunology; Biochemistry; Genetics; Gene; Immune system; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003534395,0.0003225258,0.001182933,0.00006071061,0.00003064193,0.00000339185,0.0005515536,0.0004162276,0.00008159565],"category_scores_gemma":[0.0000385362,0.0002134976,0.0005993989,0.0001019539,0.0001714931,0.000003256718,0.0003377311,0.00009062664,0.000001179118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000377863,"about_ca_system_score_gemma":0.0003104954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001095898,"about_ca_topic_score_gemma":0.000004227763,"domain_scores_codex":[0.9983193,0.0001555321,0.0005208035,0.0004212741,0.0003587992,0.0002242368],"domain_scores_gemma":[0.9984028,0.00002834042,0.0006625816,0.0007317525,0.00008666486,0.00008781994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004778587,0.00007879522,0.00004357239,0.005411404,0.0002412395,2.907711e-7,0.0000374334,0.000001458167,0.8439634,0.0000225808,0.002632444,0.1475196],"study_design_scores_gemma":[0.000203923,0.00004983274,0.00003255313,0.0008307893,0.0007780089,0.000006264173,0.00003321448,3.424611e-7,0.6018324,0.0000409257,0.3960317,0.0001599854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005143158,0.9927707,0.00004526715,0.000006147852,0.0005785375,0.0004916328,0.0008220516,0.000002626572,0.0001399018],"genre_scores_gemma":[0.02466574,0.9742677,0.000101223,0.00001225128,0.0002873283,0.00009854716,0.0002463513,0.00005263697,0.0002682264],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3933993,"threshold_uncertainty_score":0.8706177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03879624899290553,"score_gpt":0.2892594617571881,"score_spread":0.2504632127642826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}