{"id":"W2156567043","doi":"10.1093/carcin/bgv028","title":"Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression","year":2015,"lang":"en","type":"review","venue":"Carcinogenesis","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Western University; Health Canada; Dalhousie University","funders":"National Institute of Environmental Health Sciences; National Cancer Institute","keywords":"Evasion (ethics); Cancer; Growth inhibition; Cancer cell; Biology; Retinoblastoma; Retinoblastoma protein; Growth factor; Cell growth; Cell biology; Cancer research; Immunology; Biochemistry; Genetics; Gene; Immune system; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001989867,0.000605134,0.0006965894,0.001560312,0.0002403627,0.0006410864,0.0004382143,0.0006040757,0.002756996],"category_scores_gemma":[0.0002088664,0.0001814774,0.0003580966,0.0009202457,0.0003284571,0.0006482691,0.0004786854,0.0009118835,0.001191368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005403828,"about_ca_system_score_gemma":0.0005734895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006644745,"about_ca_topic_score_gemma":0.001348316,"domain_scores_codex":[0.9999139,0.00001193783,0.00001054921,0.00001618108,0.00003653762,0.0000107736],"domain_scores_gemma":[0.9999135,0.00003071301,0.00001585043,0.00000432605,0.00002539415,0.00001030773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008575508,0.0000816906,0.000371546,0.0198823,0.0001288385,0.0005463475,0.00009834241,0.0008906393,0.02539301,0.01444271,0.02225847,0.9158204],"study_design_scores_gemma":[0.000006657734,0.00007683638,0.0007929524,0.0009539039,0.00007161644,0.001272476,0.00004429417,0.00006534284,0.005577926,0.002165376,0.9889558,0.00001669194],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005809102,0.9943493,0.0006239488,0.0003245489,0.0002424478,0.00000937557,0.00006928389,0.00003080985,0.003769437],"genre_scores_gemma":[0.002854786,0.9946688,0.0003888612,0.0001932835,0.0001011395,0.00001080143,0.00006064234,0.000003379243,0.001718265],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002756996,"threshold_uncertainty_score":0.009223044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03879624899290553,"score_gpt":0.2892594617571881,"score_spread":0.2504632127642826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}