{"id":"W2156586149","doi":"10.7150/thno.4479","title":"Monitoring Photosensitizer Uptake Using Two Photon Fluorescence Lifetime Imaging Microscopy","year":2012,"lang":"en","type":"article","venue":"Theranostics","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"","keywords":"Photosensitizer; Fluorescence; Photodynamic therapy; Fluorescence microscope; Microscopy; Biophysics; Cytoplasm; Fluorescence-lifetime imaging microscopy; Intracellular; Chemistry; Phototoxicity; Two-photon excitation microscopy; Absorption (acoustics); Photochemistry; Optics; Biology; In vitro; Biochemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003511444,0.0002760429,0.0002806676,0.0003418846,0.0001763958,0.0003262855,0.0002921127,0.0004957807,0.0009491841],"category_scores_gemma":[0.0003315659,0.0001493996,0.000184765,0.0003007233,0.0001920939,0.0005097764,0.0001776106,0.0005268676,0.0002672213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005308128,"about_ca_system_score_gemma":0.0002329488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001360548,"about_ca_topic_score_gemma":0.001267124,"domain_scores_codex":[0.9998558,0.00002616533,0.000007416345,0.00004393195,0.00003861115,0.00002807925],"domain_scores_gemma":[0.999808,0.00009446394,0.00003588392,0.0000130785,0.0000353808,0.00001318377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006249173,0.00001731182,0.0001735135,0.00001851536,0.000001854359,0.00001380569,0.00002362511,0.0001945072,0.9981686,0.00007527359,0.0000160767,0.001234407],"study_design_scores_gemma":[0.00000766189,0.0001506602,0.002299329,0.000002545974,0.000007317813,0.00005920472,0.00002711919,0.01064931,0.9863923,0.00005616376,0.000337939,0.00001049428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955933,0.0004342071,0.04214248,0.00004636142,0.000008460259,0.00004730929,0.0001694818,0.0002097843,0.001008964],"genre_scores_gemma":[0.9427608,0.0009329735,0.05243942,0.00004448213,0.000008448349,0.0001554005,0.0002131824,0.00005455957,0.00339073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001360548,"threshold_uncertainty_score":0.003851295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02987370290301818,"score_gpt":0.3573130956145545,"score_spread":0.3274393927115364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}