{"id":"W2156654723","doi":"10.1002/hed.21052","title":"Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib","year":2009,"lang":"en","type":"article","venue":"Head & Neck","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Lapatinib; Fluorescence in situ hybridization; Polysomy; Epidermal growth factor receptor; Immunohistochemistry; Tyrosine-kinase inhibitor; Salivary gland cancer; Gene duplication; Medicine; Pathology; Cytokeratin; Internal medicine; Adenoid cystic carcinoma; Cancer research; Oncology; Biology; Trastuzumab; Cancer; Salivary gland; Gene; Breast cancer; Carcinoma; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002147689,0.0001972854,0.0002344837,0.0005313653,0.0002167333,0.0002628604,0.0001475367,0.0002810642,0.0005069047],"category_scores_gemma":[0.0005446832,0.000102829,0.0001744252,0.0003763709,0.0001989161,0.0001750727,0.0001512792,0.0002306083,0.00007630231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003332032,"about_ca_system_score_gemma":0.0001745688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008766175,"about_ca_topic_score_gemma":0.001222179,"domain_scores_codex":[0.9998887,0.00002142924,0.00001357322,0.00002192487,0.00002673946,0.00002768594],"domain_scores_gemma":[0.9997367,0.00007049095,0.00009579392,0.000009841427,0.00002593185,0.00006108062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006574312,0.00004636966,0.981851,0.00001597643,0.00002864475,0.002707089,0.0001369064,0.0001489993,0.01020781,0.00001671124,0.00008809567,0.004094849],"study_design_scores_gemma":[0.0000435877,0.0008090684,0.9822794,0.000005372258,0.00006211017,0.01248534,0.0002399085,0.0009225165,0.002746672,0.00004344752,0.0003571137,0.000005387877],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995611,0.0001437916,0.00004659366,0.00001635398,0.000001325197,0.000003072367,0.00002889118,0.000002563971,0.0001963122],"genre_scores_gemma":[0.999837,0.00003959641,0.00004366144,0.00000797244,0.000002481158,0.000002388438,0.00004137036,4.343236e-7,0.00002499821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008766175,"threshold_uncertainty_score":0.002417564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105473938005218,"score_gpt":0.2438213341301918,"score_spread":0.23327394032967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}