{"id":"W2156654723","doi":"10.1002/hed.21052","title":"Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib","year":2009,"lang":"en","type":"article","venue":"Head & Neck","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Lapatinib; Fluorescence in situ hybridization; Polysomy; Epidermal growth factor receptor; Immunohistochemistry; Tyrosine-kinase inhibitor; Salivary gland cancer; Gene duplication; Medicine; Pathology; Cytokeratin; Internal medicine; Adenoid cystic carcinoma; Cancer research; Oncology; Biology; Trastuzumab; Cancer; Salivary gland; Gene; Breast cancer; Carcinoma; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007172053,0.0001581901,0.0004493695,0.000354003,0.00002256268,0.00001015786,0.00003186234,0.00003509399,0.00001165233],"category_scores_gemma":[0.00001386487,0.0001052743,0.00002828526,0.000993171,0.00003214696,0.0000753908,0.000005928683,0.00005769746,0.00000128177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000714368,"about_ca_system_score_gemma":0.00003548052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008390467,"about_ca_topic_score_gemma":0.0006949908,"domain_scores_codex":[0.9989381,0.00004299322,0.0003163107,0.0003056455,0.0002235268,0.0001734652],"domain_scores_gemma":[0.9994516,0.00003286563,0.00012691,0.0002266499,0.00008277551,0.00007914063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009372798,0.001286112,0.9958076,0.00002491951,0.0001054922,0.0000864812,0.0002197664,0.00011979,0.0003053369,0.00003180095,0.000006765334,0.001068638],"study_design_scores_gemma":[0.004855513,0.001391053,0.9885378,0.0003583583,0.0003832537,0.000007361637,0.00002550521,0.0003548972,0.003964109,0.000006627451,0.00000233309,0.0001131338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990817,0.0001024923,0.00001352848,0.0001427544,0.000003961305,0.0004910515,0.00002006999,0.0000166516,0.000127747],"genre_scores_gemma":[0.9985148,0.00006110744,0.0006236285,0.00008468055,0.000007494641,0.00002459847,0.0006639565,0.00001110846,0.000008656193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007269763,"threshold_uncertainty_score":0.429296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105473938005218,"score_gpt":0.2438213341301918,"score_spread":0.23327394032967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}