{"id":"W2156658768","doi":"10.1016/j.chom.2011.07.004","title":"Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus","year":2011,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":415,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Institute of Allergy and Infectious Diseases; Division of Chemistry; National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Calprotectin; Microbiology; Superoxide; Staphylococcus aureus; Biology; Superoxide dismutase; Antimicrobial; Bacteria; Biochemistry; Oxidative stress; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001565129,0.0003084592,0.0004290168,0.0001446997,0.000183344,0.0003482256,0.0004692578,0.0003935204,0.001557092],"category_scores_gemma":[0.0003330037,0.0001474567,0.0001591594,0.0001382136,0.0003068197,0.0002179713,0.0002155238,0.0007164149,0.0002608956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005677065,"about_ca_system_score_gemma":0.0005983094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001886614,"about_ca_topic_score_gemma":0.005125796,"domain_scores_codex":[0.9998612,0.00002903713,0.00001119112,0.00001885619,0.00003161536,0.00004809378],"domain_scores_gemma":[0.9998491,0.00004264179,0.00002575813,0.0000244423,0.00001573246,0.00004236332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001927257,0.0001429393,0.0001681551,0.00004489744,0.000009122077,0.00006373427,0.00001613662,0.0001155698,0.9948364,0.0001574554,0.0001777046,0.002340652],"study_design_scores_gemma":[0.0001487653,0.0007156048,0.002557394,0.000005865891,0.00001468563,0.000124492,0.00001799721,0.0009951697,0.9942489,0.00005259853,0.001114172,0.000004371583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969919,0.0009669167,0.0007191222,0.0001985019,0.00004434075,0.00002110876,0.0001423882,0.00006943562,0.0008461875],"genre_scores_gemma":[0.9959887,0.0003949881,0.0009681059,0.00008177883,0.00001972408,0.0000238967,0.0002950023,0.00001349418,0.002214465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001886614,"threshold_uncertainty_score":0.005208969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00996472848391964,"score_gpt":0.1996938036007489,"score_spread":0.1897290751168293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}