{"id":"W2156658768","doi":"10.1016/j.chom.2011.07.004","title":"Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus","year":2011,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":415,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Institute of Allergy and Infectious Diseases; Division of Chemistry; National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Calprotectin; Microbiology; Superoxide; Staphylococcus aureus; Biology; Superoxide dismutase; Antimicrobial; Bacteria; Biochemistry; Oxidative stress; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001630015,0.000230852,0.0002190895,0.00004764073,0.00008129887,0.00002039699,0.0001664698,0.0002152643,0.0001073059],"category_scores_gemma":[0.0000182207,0.0002271911,0.0001392529,0.00009166797,0.00008120901,0.00001014077,0.0001032401,0.000131827,0.00001864022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000200796,"about_ca_system_score_gemma":0.00008558948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002351486,"about_ca_topic_score_gemma":0.00005324227,"domain_scores_codex":[0.9987264,0.00007024881,0.0003756992,0.0004158265,0.00009233393,0.0003194908],"domain_scores_gemma":[0.9993081,0.000004638513,0.0001612899,0.0003122134,0.0001206353,0.00009313777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001421001,0.0001656873,0.0001424715,0.00005014048,0.00002617909,0.0000032139,0.0002337647,0.000002473701,0.9988165,0.00001636063,0.0003090208,0.00009205112],"study_design_scores_gemma":[0.0005931077,0.0005121838,0.00007823272,0.00003352944,0.00002437788,0.000004084744,0.0001314919,0.000002801083,0.991661,0.00001731295,0.006692185,0.0002497334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951175,0.001090105,0.002500637,0.00001170911,0.0002078181,0.0003922317,0.00008654519,0.00001453032,0.0005789353],"genre_scores_gemma":[0.9977208,0.0001148372,0.001366925,0.00006341258,0.0002281958,0.00001561621,0.0001734367,0.0000380383,0.0002787727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007155577,"threshold_uncertainty_score":0.9264584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00996472848391964,"score_gpt":0.1996938036007489,"score_spread":0.1897290751168293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}