{"id":"W2156721227","doi":"10.1002/iub.489","title":"How a neutral evolutionary ratchet can build cellular complexity","year":2011,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Dalhousie University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Centre National d’Etudes Spatiales; Canadian Institute for Advanced Research","keywords":"Constructive; Function (biology); Process (computing); Component (thermodynamics); Selection (genetic algorithm); Biology; Computer science; Ratchet; Cognitive science; Evolutionary biology; Artificial intelligence; Psychology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000146703,0.0005441097,0.0008917832,0.00008735061,0.0001302105,0.00004921058,0.0005745046,0.0007158073,0.00005246233],"category_scores_gemma":[0.0000808503,0.0005072135,0.0006531989,0.0001616683,0.0002784736,0.000002840609,0.0002875364,0.0003549113,0.00005565771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006078064,"about_ca_system_score_gemma":0.000792751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006647885,"about_ca_topic_score_gemma":0.0001584689,"domain_scores_codex":[0.9979628,0.0002327442,0.0004316114,0.0007243103,0.0001491796,0.0004993935],"domain_scores_gemma":[0.9983582,0.00001101167,0.0002964594,0.0008666341,0.0001106477,0.0003570134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002100135,0.001763151,0.0004408777,0.03022687,0.004360169,0.0001452813,0.0002461326,0.00007407748,0.001585453,0.03139437,0.5029051,0.4266485],"study_design_scores_gemma":[0.0002034501,0.0001079393,0.00003365851,0.0002931312,0.0002575026,0.00004659532,0.00001394644,0.00002481516,0.00002320428,0.000151117,0.9982781,0.0005665628],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001176478,0.99586,0.0009396455,0.0001666539,0.0005292485,0.0005218909,0.0004975465,0.00004061016,0.001326737],"genre_scores_gemma":[0.0005165669,0.9867277,0.001182137,0.0003085244,0.0009853845,0.00008649898,0.003124038,0.00009038716,0.006978741],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.495373,"threshold_uncertainty_score":0.9997379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0564455221243998,"score_gpt":0.2879806405569278,"score_spread":0.2315351184325281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}