{"id":"W2156769390","doi":"10.1021/ac202978r","title":"Electrochemical Sensing of Aptamer-Facilitated Virus Immunoshielding","year":2011,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Chemistry; Oncolytic virus; Vesicular stomatitis virus; Virology; Dielectric spectroscopy; Detection limit; Virus; DNA; Molecular biology; Combinatorial chemistry; Electrochemistry; Chromatography; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005170228,0.0007357716,0.0004256835,0.0003093634,0.0001305438,0.0004062066,0.0008208902,0.0008672258,0.0004753816],"category_scores_gemma":[0.0008311598,0.0002859263,0.0002139896,0.0003367384,0.0002703325,0.0004297381,0.0003863554,0.0006722308,0.00031622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004804073,"about_ca_system_score_gemma":0.0001950561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004612892,"about_ca_topic_score_gemma":0.0007374054,"domain_scores_codex":[0.9992363,0.0001521941,0.0000420398,0.0002045936,0.0002869842,0.00007786394],"domain_scores_gemma":[0.9996512,0.0001324762,0.00005823888,0.00002062755,0.0001073381,0.00003008348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001932243,0.000008966279,0.00009176874,0.00003871724,0.000003796884,0.0000230014,0.00002195003,0.00008680952,0.9976206,0.00005994083,0.00002751251,0.001997582],"study_design_scores_gemma":[0.000004820345,0.00005285147,0.0003765637,0.000002638522,0.000005481569,0.00008591577,0.00001627169,0.00236128,0.9964752,0.00003458345,0.0005789677,0.000005458038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.844315,0.005702148,0.1452275,0.0003793029,0.0003154434,0.0001543442,0.0004636479,0.0007683297,0.002674263],"genre_scores_gemma":[0.9031854,0.002919505,0.08974707,0.0002749637,0.00006093873,0.0001780195,0.0002941191,0.0000303229,0.00330963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008672258,"threshold_uncertainty_score":0.00348568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02583059091034777,"score_gpt":0.2848864594137502,"score_spread":0.2590558685034024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}