{"id":"W2156769390","doi":"10.1021/ac202978r","title":"Electrochemical Sensing of Aptamer-Facilitated Virus Immunoshielding","year":2011,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Chemistry; Oncolytic virus; Vesicular stomatitis virus; Virology; Dielectric spectroscopy; Detection limit; Virus; DNA; Molecular biology; Combinatorial chemistry; Electrochemistry; Chromatography; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002182351,0.0001841498,0.0002278436,0.00002688502,0.00004297901,0.000008712304,0.0002762566,0.0002366506,0.0003964313],"category_scores_gemma":[0.0002254199,0.0001861256,0.0001751877,0.0001857991,0.0003694501,0.000003258821,0.0001213622,0.0002380779,0.00001775222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002353745,"about_ca_system_score_gemma":0.0001048216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000409319,"about_ca_topic_score_gemma":0.000008282836,"domain_scores_codex":[0.9986321,0.00003775485,0.000307985,0.0003850311,0.0002231568,0.0004139855],"domain_scores_gemma":[0.999097,0.00002518221,0.00006520184,0.000513424,0.0001489365,0.0001502306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001071221,0.00008304496,0.0002064123,0.00003377456,0.000138085,0.000006763239,0.00003435036,9.651019e-7,0.9975637,0.00001127043,0.0001925827,0.0006578725],"study_design_scores_gemma":[0.0003354085,0.000374138,0.00004940739,0.00001308337,0.00002816324,0.00001730523,0.00008137884,0.0003239062,0.9980302,0.0001040461,0.0004461743,0.0001967366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882722,0.0003836853,0.00073655,0.0000348639,0.00001451252,0.00006187515,0.000008871026,0.00001894017,0.01046845],"genre_scores_gemma":[0.9983533,0.00008454319,0.0006046952,0.00006937203,0.00008958059,0.000002474777,0.00006150656,0.00002585091,0.0007086998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01008103,"threshold_uncertainty_score":0.7589981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02583059091034777,"score_gpt":0.2848864594137502,"score_spread":0.2590558685034024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}