{"id":"W2156817850","doi":"10.1517/13543776.16.7.977","title":"TRPV1 antagonists: a survey of the patent literature","year":2006,"lang":"en","type":"article","venue":"Expert Opinion on Therapeutic Patents","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"TRPV1; Pharmacology; Medicine; Clinical trial; Computational biology; Business; Biology; Receptor; Internal medicine; Transient receptor potential channel","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186865,0.0002070237,0.0001949581,0.00006526081,0.0001982566,0.00005085621,0.0004218758,0.0001140005,0.00006065092],"category_scores_gemma":[0.00004586388,0.0001156783,0.0001378459,0.000401033,0.0001246839,0.00007154699,0.00005914019,0.0001749091,0.00003445338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004014384,"about_ca_system_score_gemma":0.00002922208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002825075,"about_ca_topic_score_gemma":0.000003350801,"domain_scores_codex":[0.9981031,0.0004616485,0.0003139573,0.0003667472,0.0004703767,0.0002841806],"domain_scores_gemma":[0.9992791,0.0001149956,0.0001738212,0.0003172311,0.00006951005,0.00004530884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005184903,0.001947365,0.01143773,0.00003517559,0.0000356208,0.00000797277,0.002358221,0.0002162471,0.9503678,0.003849259,0.008774337,0.02045176],"study_design_scores_gemma":[0.00111081,0.0001845598,0.07784609,0.0002067431,0.000001339272,0.00001233234,0.0000356782,0.0004000927,0.8935774,0.0006345623,0.02570167,0.0002887166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665974,0.007726748,0.0001931773,0.002668049,0.01917282,0.001212713,0.0003504867,0.0001854125,0.001893163],"genre_scores_gemma":[0.9965706,0.001191929,0.000006937473,0.001436318,0.0001756508,0.00002085256,0.00002473777,0.00002588163,0.0005470462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06640837,"threshold_uncertainty_score":0.4717225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1222570584195841,"score_gpt":0.3083448457455742,"score_spread":0.1860877873259901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}