{"id":"W2156863059","doi":"10.1186/gb-2012-13-4-r31","title":"Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel","year":2012,"lang":"en","type":"article","venue":"Genome biology","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Medical Research Council; Fondation Leducq; Norwegian Biodiversity Information Centre; Grantová Agentura České Republiky; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; British Heart Foundation","keywords":"Biology; Genetics; Transcriptome; Human genetics; Inbred strain; Evolutionary biology; Recombinant DNA; Computational biology; Gene; Biotechnology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002317377,0.0003440347,0.0002599078,0.0008162771,0.0001457868,0.0002211784,0.0001843267,0.0002043755,0.001554494],"category_scores_gemma":[0.0002710874,0.000177195,0.0002813122,0.0002999487,0.0002027728,0.00007612846,0.0002324476,0.0004285272,0.0002740131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001588195,"about_ca_system_score_gemma":0.0001066301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005439465,"about_ca_topic_score_gemma":0.0009945489,"domain_scores_codex":[0.9996982,0.00004720141,0.00003049366,0.00009272679,0.00008530059,0.00004610988],"domain_scores_gemma":[0.9995335,0.0001031638,0.0002106814,0.0000453575,0.00002503731,0.00008232466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001456402,0.00001969203,0.003067613,0.00001378073,0.0000258507,0.00004934122,0.00001967351,0.00003966131,0.9957892,0.00003292362,0.00001449259,0.000782037],"study_design_scores_gemma":[0.00004876572,0.0005267321,0.7101953,0.00001713965,0.0002831279,0.001498177,0.0000992006,0.001344671,0.2845988,0.0001668153,0.001194457,0.00002683639],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971841,0.0001411201,0.001211626,0.00001740682,0.000002746586,0.00001024454,0.001126676,0.00003384297,0.0002723032],"genre_scores_gemma":[0.9924253,0.0001816851,0.002564906,0.00003585041,0.000006884559,0.00003285113,0.004050062,0.00005644985,0.0006458945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001554494,"threshold_uncertainty_score":0.005200267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03558858614662004,"score_gpt":0.2444446093903225,"score_spread":0.2088560232437024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}