{"id":"W2156873202","doi":"10.1093/nar/gks903","title":"Regulation of human Dicer by the resident ER membrane protein CLIMP-63","year":2012,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dicer; Biology; Cell biology; Endoplasmic reticulum; microRNA; Ribonuclease III; Messenger RNA; Molecular biology; RNA; RNA interference; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001089163,0.00008946376,0.00008883303,0.00005630957,0.0002197306,0.00002838321,0.0002570891,0.0001265177,0.0006286074],"category_scores_gemma":[0.0001639038,0.00006489029,0.00006901783,0.0001658949,0.0002703524,0.00001131706,0.0001637497,0.0001361899,0.00003953849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002279215,"about_ca_system_score_gemma":0.00004808189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006756419,"about_ca_topic_score_gemma":0.00001049634,"domain_scores_codex":[0.9984066,0.0002950564,0.0002056646,0.0001928587,0.0005504376,0.0003493557],"domain_scores_gemma":[0.9990503,0.00001805935,0.00006002792,0.0005258911,0.0001981641,0.0001475746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000106469,0.00008506406,0.005891392,0.00002291841,0.00001788086,1.696176e-7,0.0000974549,0.000002902274,0.9616019,0.0009688766,0.03030793,0.0008970302],"study_design_scores_gemma":[0.0006709437,0.0002026333,0.1085578,0.00002032032,0.00001024693,0.000002393177,0.0002611236,0.00004902733,0.8219815,0.0003281774,0.0677773,0.0001384937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888675,0.0006497253,0.00004418226,0.000723258,0.00002942974,0.0004275292,0.00001202683,0.000008427765,0.009237923],"genre_scores_gemma":[0.9846858,0.00002157397,0.00004467253,0.00006164363,0.0002647072,0.00004924235,0.00008477584,0.000020588,0.014767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1396203,"threshold_uncertainty_score":0.6882811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03634270706163198,"score_gpt":0.3502568750941911,"score_spread":0.3139141680325591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}