{"id":"W2156907566","doi":"10.1084/jem.20011845","title":"CD4+ T Cells from Glutamic Acid Decarboxylase (GAD)65-specific T Cell Receptor Transgenic Mice Are Not Diabetogenic and Can Delay Diabetes Transfer","year":2002,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging","keywords":"Insulitis; NOD mice; T-cell receptor; Biology; T cell; Glutamate decarboxylase; Adoptive cell transfer; Nod; Immunology; Molecular biology; Endocrinology; Immune system; Diabetes mellitus; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002641351,0.0002784326,0.0003963821,0.00005627094,0.0001145367,0.00001659075,0.0003257398,0.0001380648,0.0003808547],"category_scores_gemma":[0.00001459819,0.0001899083,0.000154656,0.0001039517,0.0002511112,0.00001077204,0.00003325364,0.000234999,0.000007721757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003737707,"about_ca_system_score_gemma":0.00001572717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002275201,"about_ca_topic_score_gemma":0.00001166275,"domain_scores_codex":[0.9984838,0.0001632628,0.0004722959,0.0002288041,0.0002916705,0.0003601733],"domain_scores_gemma":[0.9992466,0.00006537244,0.0001911982,0.0002216749,0.00006055707,0.0002145818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001180279,0.0001988655,0.0005259708,0.000007485783,0.0001702875,0.000002684111,0.001279687,0.00001573047,0.9933088,6.787986e-7,0.003738754,0.00063303],"study_design_scores_gemma":[0.003082114,0.001095878,0.0003507723,0.00008107402,0.0001492516,0.000004123865,0.002455149,0.00003421227,0.9884863,0.00001002349,0.004028345,0.0002227008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924218,0.07410288,0.00002946102,0.000910108,0.0004062559,0.0001497103,0.00005798244,0.000005754447,0.0001198755],"genre_scores_gemma":[0.9905266,0.007783799,0.00006020365,0.001000608,0.0004658576,0.000005191571,0.00002471977,0.00004190419,0.00009111885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06631908,"threshold_uncertainty_score":0.7744237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009657450070664538,"score_gpt":0.2044394661652228,"score_spread":0.1947820160945583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}