{"id":"W2156921701","doi":"10.3389/fphar.2013.00057","title":"Systemic cancer therapy: achievements and challenges that lie ahead","year":2013,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Cancer; Medicine; Systemic therapy; Intensive care medicine; Internal medicine; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005119418,0.0001169263,0.0002430839,0.0001188029,0.00004087013,0.000007113118,0.00004912562,0.00006944266,0.0003156544],"category_scores_gemma":[0.000001781313,0.00009178235,0.0000250504,0.00005923917,0.00006022697,0.00008797606,0.00001944126,0.0001063258,0.00001333486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001831948,"about_ca_system_score_gemma":0.00007021033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002104409,"about_ca_topic_score_gemma":0.00001091035,"domain_scores_codex":[0.9993061,0.00004728186,0.0001248713,0.0002164246,0.00007999334,0.0002252634],"domain_scores_gemma":[0.9997333,0.00001716872,0.00004670278,0.00008213255,0.00002996916,0.00009069016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002248245,0.0003923485,0.5072507,0.0002555944,0.001164007,0.00005122102,0.00289414,0.000007917562,0.005533164,0.00004617712,0.1174911,0.3646888],"study_design_scores_gemma":[0.03365133,0.001089461,0.6814349,0.0003915859,0.0009757094,0.0001262476,0.005563672,0.0009115215,0.007124384,0.001093481,0.2670067,0.0006309731],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8347214,0.1493386,0.00005565734,0.01015352,0.002402539,0.001198743,0.000008975188,0.00003992295,0.002080633],"genre_scores_gemma":[0.8979324,0.09780473,0.0004827491,0.00166602,0.0001414667,0.0007888146,0.000008071496,0.00001720971,0.001158615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3640578,"threshold_uncertainty_score":0.3742776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03944102994547627,"score_gpt":0.3435497272443555,"score_spread":0.3041086972988792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}