{"id":"W2156923721","doi":"10.1093/jac/dkr110","title":"Ceftaroline pharmacodynamic activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model","year":2011,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Health Sciences Centre","funders":"","keywords":"Staphylococcus aureus; Vancomycin; Methicillin-resistant Staphylococcus aureus; Microbiology; Medicine; Pharmacodynamics; Cephalosporin; Antibiotics; Cmax; Pharmacokinetics; Pharmacology; Bacteria; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002217164,0.0003197406,0.0004358088,0.0001245953,0.00007814515,0.0003558655,0.000200344,0.0002790986,0.0009296197],"category_scores_gemma":[0.0003303662,0.0001127422,0.0002938322,0.0001407963,0.0001164709,0.0001880831,0.00008062186,0.0003930211,0.0001987849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002668684,"about_ca_system_score_gemma":0.0002716932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001159005,"about_ca_topic_score_gemma":0.001715395,"domain_scores_codex":[0.9997818,0.00007000546,0.00002021864,0.00003462991,0.00005535554,0.00003805187],"domain_scores_gemma":[0.9996603,0.00009006946,0.0001071381,0.00002881196,0.00007510536,0.00003860264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003021635,0.0007267619,0.002595281,0.0001805487,0.00005812066,0.00007989853,0.00003300457,0.0008130244,0.9859684,0.00003341216,0.0001864619,0.00630355],"study_design_scores_gemma":[0.0002292071,0.04158796,0.03153526,0.00002681593,0.0002141856,0.0007195055,0.0001068278,0.005319122,0.9175465,0.00005432384,0.002632829,0.00002751849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960945,0.002138925,0.0006075504,0.00006148839,0.00002720829,0.00002955525,0.000259058,0.0000185541,0.0007631626],"genre_scores_gemma":[0.9969698,0.001179371,0.0006608207,0.000044646,0.00002456016,0.00002279192,0.0003606223,0.000005792288,0.0007314723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001159005,"threshold_uncertainty_score":0.003109872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05205502738040416,"score_gpt":0.3198396236257582,"score_spread":0.2677845962453541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}