{"id":"W2156932717","doi":"10.1074/jbc.m001797200","title":"Macrophage Colony-stimulating Factor Rapidly Enhances β-Migrating Very Low Density Lipoprotein Metabolism in Macrophages through Activation of a Gi/o Protein Signaling Pathway","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; National Institutes of Health; Pfizer; American Heart Association","keywords":"Macrophage; Cell biology; Macrophage colony-stimulating factor; Signal transduction; Metabolism; Chemistry; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373453,0.0004805354,0.000292213,0.0001993766,0.00009827308,0.0002259427,0.0001166448,0.0002114496,0.0005784798],"category_scores_gemma":[0.00009511541,0.0001047222,0.0003012648,0.0001189489,0.0001883093,0.0001377142,0.0002497592,0.0004631344,0.0002210179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002219446,"about_ca_system_score_gemma":0.0001907751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000507489,"about_ca_topic_score_gemma":0.000777745,"domain_scores_codex":[0.9998887,0.00002357662,0.000008251031,0.00001255248,0.00002407044,0.00004291592],"domain_scores_gemma":[0.9999285,0.00001001695,0.00001653906,0.000007080414,0.00001117185,0.00002670419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002658715,0.00003516463,0.0001787615,0.00005175343,0.000006081855,0.00009293798,0.00001613793,0.00001500441,0.9980562,0.00002925491,0.00004556639,0.001207332],"study_design_scores_gemma":[0.00006962935,0.001263049,0.01740391,0.00002654535,0.00003194672,0.0003774228,0.00007079455,0.0005111872,0.9762459,0.0000720594,0.003921248,0.000006319792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939937,0.0034178,0.000943593,0.0001582211,0.00003761891,0.00003463301,0.0001995205,0.00006758707,0.001147398],"genre_scores_gemma":[0.9937553,0.002228827,0.001950055,0.000188594,0.00002848666,0.00007731331,0.0003574379,0.0000125466,0.001401409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005784798,"threshold_uncertainty_score":0.001935244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01543494633700323,"score_gpt":0.2443162924503228,"score_spread":0.2288813461133196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}