{"id":"W2156979070","doi":"10.1124/pr.109.001370","title":"Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery","year":2009,"lang":"en","type":"review","venue":"Pharmacological Reviews","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":1061,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Vasoactive intestinal peptide; Receptor; Secretin; Biology; Cyclase; Adenylyl cyclase; Adenylate kinase; Anterior pituitary; Pituitary adenylate cyclase-activating peptide; Secretin family; Internal medicine; Endocrinology; Neuropeptide; Hormone; Biochemistry; Pancreas","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008920897,0.001171652,0.001650667,0.001225295,0.0003126078,0.001465088,0.001098002,0.001779119,0.00229479],"category_scores_gemma":[0.0009496196,0.0003107503,0.0004226149,0.00211648,0.001068647,0.00254873,0.0009357802,0.002268276,0.002109942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008538301,"about_ca_system_score_gemma":0.001595007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00127589,"about_ca_topic_score_gemma":0.002369717,"domain_scores_codex":[0.9997759,0.00002825478,0.00003364233,0.00004949456,0.00008318087,0.00002945607],"domain_scores_gemma":[0.9995289,0.00020593,0.00006459317,0.0000161989,0.0001238573,0.00006058344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002940023,0.00008602171,0.0002049603,0.01150797,0.00007782071,0.0006501123,0.0001155849,0.0003383853,0.006645631,0.005804121,0.0364265,0.937849],"study_design_scores_gemma":[0.00004054884,0.00008546482,0.0008649358,0.002007734,0.00008881234,0.001565788,0.0001176845,0.00006862186,0.000926176,0.002766243,0.9914417,0.00002630751],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001262881,0.9985301,0.0001312703,0.0002656922,0.000382516,0.00000231124,0.00001001478,0.000003849769,0.0005480127],"genre_scores_gemma":[0.0007092786,0.9977381,0.0002218877,0.0003087241,0.0004226319,0.00000438212,0.0000222676,0.000001425729,0.000571224],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00229479,"threshold_uncertainty_score":0.00767678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1492287744706844,"score_gpt":0.3889958625583233,"score_spread":0.2397670880876389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}