{"id":"W2157006065","doi":"10.1074/jbc.m309027200","title":"Regulation of Tension-induced Mechanotranscriptional Signals by the Microtubule Network in Fibroblasts","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canadian Institutes of Health Research","funders":"","keywords":"Filamin; Cell biology; Microtubule; Focal adhesion; Cytoskeleton; Extracellular matrix; Actin; Tubulin; Chemistry; Biology; Signal transduction; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005167478,0.000125727,0.00007783458,0.0001141487,0.0001324021,0.0001599562,0.00008343317,0.00009779463,0.0004920554],"category_scores_gemma":[0.00005419078,0.00007577321,0.00007699016,0.0000592147,0.00006554715,0.00008812484,0.00009254363,0.0001464894,0.0001303099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002922581,"about_ca_system_score_gemma":0.0000827197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009590585,"about_ca_topic_score_gemma":0.001546755,"domain_scores_codex":[0.9999616,0.000006874709,0.000002966689,0.0000071172,0.00001049464,0.00001087916],"domain_scores_gemma":[0.9999715,0.000006003908,0.000007571578,0.00000266701,0.000005243588,0.000006909415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006876783,0.000009421566,0.0002756188,0.00001871566,0.000002508251,0.00004592758,0.00001169396,0.00005035679,0.9980075,0.00008004757,0.00003220987,0.001397246],"study_design_scores_gemma":[0.00003348124,0.0001919005,0.02762922,0.00001078084,0.00001078289,0.0002783933,0.00007153142,0.003421965,0.9651749,0.0001261391,0.003044012,0.000006973675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958581,0.001464614,0.001005687,0.00005547406,0.00001469398,0.00001271093,0.0001394548,0.00002124952,0.001427941],"genre_scores_gemma":[0.9976633,0.0006904685,0.0005377576,0.00001628839,0.000004931192,0.00002326867,0.00009269881,0.0000028113,0.000968606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009590585,"threshold_uncertainty_score":0.002120495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01743841327365499,"score_gpt":0.2351048858521117,"score_spread":0.2176664725784567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}