{"id":"W2157028755","doi":"10.1534/genetics.105.045641","title":"The Purine Synthesis Gene <i>Prat2</i> Is Required for Drosophila Metamorphosis, as Revealed by Inverted-Repeat-Mediated RNA Interference","year":2005,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick","funders":"Canadian Institutes of Health Research; New Brunswick Innovation Foundation","keywords":"RNA interference; Biology; Drosophila melanogaster; Genetics; Gene; Phenotype; Transgene; Metamorphosis; RNA; Larva; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002773815,0.0003177578,0.0002482826,0.0000371137,0.000202072,0.00007263931,0.0005291137,0.0002172888,0.00003040725],"category_scores_gemma":[0.0002555489,0.000269371,0.0001756774,0.0001292075,0.0001104916,0.000004487327,0.0001817288,0.000110652,0.00004303957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002631687,"about_ca_system_score_gemma":0.00007136112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001029107,"about_ca_topic_score_gemma":0.00005069785,"domain_scores_codex":[0.9982804,0.00005094938,0.0004395775,0.0005249154,0.0001937619,0.0005103759],"domain_scores_gemma":[0.9986731,0.0001000836,0.0001197341,0.0007758142,0.0001544486,0.0001767756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006901684,0.00004132847,0.00009621542,0.000017547,0.0001435482,8.421183e-7,0.00004359715,0.0001216113,0.9259415,0.00000913238,0.06216492,0.01135073],"study_design_scores_gemma":[0.0003926652,0.0001776658,0.00008969996,0.00001146082,0.0000756292,0.00001403913,0.00002972034,0.001065027,0.7532268,0.00003844185,0.2446069,0.0002719463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9382256,0.03014636,0.0235081,0.005315711,0.0005137638,0.001012363,0.0005106692,0.00008310726,0.0006843797],"genre_scores_gemma":[0.9823207,0.007585299,0.005737379,0.001424409,0.000535508,0.0002347387,0.0002034472,0.00007885215,0.001879623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.182442,"threshold_uncertainty_score":0.9999759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009437515793960106,"score_gpt":0.2684833557195334,"score_spread":0.2590458399255732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}