{"id":"W2157028755","doi":"10.1534/genetics.105.045641","title":"The Purine Synthesis Gene <i>Prat2</i> Is Required for Drosophila Metamorphosis, as Revealed by Inverted-Repeat-Mediated RNA Interference","year":2005,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick","funders":"Canadian Institutes of Health Research; New Brunswick Innovation Foundation","keywords":"RNA interference; Biology; Drosophila melanogaster; Genetics; Gene; Phenotype; Transgene; Metamorphosis; RNA; Larva; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007996857,0.0006687269,0.0002289992,0.0002015063,0.0002115307,0.0003594528,0.0003553422,0.0003294299,0.001435396],"category_scores_gemma":[0.0000937552,0.0002819905,0.0003714584,0.0001480391,0.0002454984,0.0001828128,0.0002745874,0.0005569732,0.001037568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176323,"about_ca_system_score_gemma":0.0001903814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006359824,"about_ca_topic_score_gemma":0.001164476,"domain_scores_codex":[0.999854,0.0000139797,0.00001165056,0.00005822781,0.00004250789,0.00001961363],"domain_scores_gemma":[0.9998845,0.00002025471,0.00004909375,0.00001576083,0.00000810582,0.00002227829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002340564,0.000003724572,0.0000705071,0.0000161248,0.000002300916,0.00005378588,0.000003338175,0.00002783311,0.9992929,0.00004686253,0.00002901628,0.0004304287],"study_design_scores_gemma":[0.00001351387,0.00005432617,0.006088881,0.00000606963,0.00001366805,0.000517175,0.000008943441,0.001029164,0.9868106,0.00002494748,0.005427206,0.000005586594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719046,0.001605482,0.01624952,0.0002200903,0.00006751795,0.00009081722,0.004369626,0.0008987383,0.004593535],"genre_scores_gemma":[0.9752073,0.0009342041,0.009022666,0.0001407829,0.00002661165,0.00009208541,0.006555328,0.0003116966,0.007709346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001435396,"threshold_uncertainty_score":0.004801869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009437515793960106,"score_gpt":0.2684833557195334,"score_spread":0.2590458399255732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}