{"id":"W2157074639","doi":"10.1093/bja/aes432","title":"Partial antagonism of propofol anaesthesia by physostigmine in rats is associated with potentiation of fast (80–200 Hz) oscillations in the thalamus","year":2012,"lang":"en","type":"article","venue":"British Journal of Anaesthesia","topic":"Anesthesia and Sedative Agents","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Concordia University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Unconsciousness; Physostigmine; Propofol; Thalamus; Anesthesia; Medicine; Cortex (anatomy); Long-term potentiation; Neuroscience; Psychology; Pharmacology; Internal medicine; Acetylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001372393,0.0006509911,0.0005770298,0.0003612965,0.0001924966,0.0002825344,0.0003346348,0.0003935806,0.002331451],"category_scores_gemma":[0.0004213164,0.00038001,0.0003766165,0.0002100052,0.0008494666,0.000513821,0.0002705447,0.001308851,0.00030202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004664284,"about_ca_system_score_gemma":0.0006335165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002081324,"about_ca_topic_score_gemma":0.004096749,"domain_scores_codex":[0.9998657,0.00001732763,0.000007031588,0.00001712551,0.00003005051,0.00006276865],"domain_scores_gemma":[0.999647,0.00005419902,0.000128982,0.00004250367,0.0000318513,0.00009546131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009009316,0.000133007,0.0006992677,0.0001018711,0.00003898099,0.0003032959,0.00008030826,0.0001069274,0.984472,0.0003421911,0.0001544983,0.004558375],"study_design_scores_gemma":[0.0006679082,0.007615315,0.07092577,0.00003545564,0.0002111116,0.0006593378,0.0003828021,0.001645826,0.9157743,0.0007715012,0.001260366,0.00005020761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972139,0.0006057944,0.0007141018,0.000206931,0.00003896403,0.00002311582,0.0001953966,0.00004199614,0.0009598597],"genre_scores_gemma":[0.9962465,0.0009069088,0.0004970056,0.00008587393,0.00002690949,0.00007059326,0.0002555683,0.00002039041,0.001890099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002331451,"threshold_uncertainty_score":0.007799506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546393355346527,"score_gpt":0.2499994043646275,"score_spread":0.2345354708111622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}