{"id":"W2157130670","doi":"10.2147/ndt.s41020","title":"Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-&amp;alpha; and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats","year":2013,"lang":"en","type":"article","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Pentoxifylline; Medicine; Endocrinology; Imipramine; Nitric oxide synthase; Hippocampus; Internal medicine; Enos; Tumor necrosis factor alpha; Serotonin; Nitric oxide; Immunostaining; Pharmacology; Immunohistochemistry; Pathology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008984077,0.0004468803,0.000391161,0.0001977482,0.0001293609,0.0001530176,0.0001760221,0.0002987897,0.0007254736],"category_scores_gemma":[0.0001090741,0.0001782392,0.0002481929,0.00009853836,0.0003105294,0.0002047752,0.0001113445,0.0006804399,0.0001266757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001838759,"about_ca_system_score_gemma":0.000227656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027556,"about_ca_topic_score_gemma":0.00244665,"domain_scores_codex":[0.9999274,0.000008071254,0.000008242637,0.00001523109,0.00001439563,0.00002666629],"domain_scores_gemma":[0.9998195,0.00001046235,0.00006649881,0.00001388794,0.00001739236,0.00007233779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00720016,0.0005520394,0.001780229,0.00008283125,0.00004132356,0.0001766684,0.00006375926,0.00006785946,0.9862748,0.00004024599,0.00007566834,0.003644409],"study_design_scores_gemma":[0.0005983332,0.0304333,0.0713713,0.00002816672,0.0001881531,0.0006498724,0.0003351881,0.001269248,0.8934737,0.00009840665,0.001528608,0.00002552405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989055,0.0005554334,0.000161216,0.00005537901,0.00002196624,0.00001080503,0.0001078873,0.00001773407,0.000164085],"genre_scores_gemma":[0.9971979,0.0007607061,0.0005553842,0.00005778535,0.00001938907,0.00004053195,0.000277678,0.000004053692,0.001086654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001027556,"threshold_uncertainty_score":0.002426982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01383505591741736,"score_gpt":0.2365430042956999,"score_spread":0.2227079483782825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}