{"id":"W2157130670","doi":"10.2147/ndt.s41020","title":"Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-α and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats","year":2013,"lang":"en","type":"article","venue":"Neuropsychiatric Disease and Treatment","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Pentoxifylline; Medicine; Endocrinology; Imipramine; Nitric oxide synthase; Hippocampus; Internal medicine; Enos; Tumor necrosis factor alpha; Serotonin; Nitric oxide; Immunostaining; Pharmacology; Immunohistochemistry; Pathology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003552155,0.0003501436,0.0003730573,0.0001886747,0.0001133776,0.00006379809,0.0001101206,0.00004288523,0.00001386402],"category_scores_gemma":[0.00007311411,0.0002367723,0.00006796642,0.0002590894,0.0002511797,0.0001641508,0.00006011811,0.0001225553,0.000002159835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002564772,"about_ca_system_score_gemma":0.00006087454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002657532,"about_ca_topic_score_gemma":0.0001249042,"domain_scores_codex":[0.9983699,0.0002332088,0.0002614083,0.0005898129,0.0002481424,0.0002975638],"domain_scores_gemma":[0.9987552,0.0005141443,0.0001817952,0.0002782059,0.00001647575,0.0002542389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002332205,0.009094764,0.05610882,0.001174376,0.0001007555,0.0002260923,0.00124458,0.000008917596,0.8161727,0.0001223115,0.0001580102,0.1132565],"study_design_scores_gemma":[0.005522538,0.001733493,0.9340497,0.00006029348,0.00007177881,0.00001261792,0.00004753143,0.0002364555,0.05782256,0.0002193261,0.00001669564,0.0002070655],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951524,0.00304338,0.000001724678,0.0001959481,0.00007300603,0.00130448,0.0001830147,0.00001833553,0.00002772731],"genre_scores_gemma":[0.9973959,0.002193973,0.00001432715,0.0002189135,0.00003615196,0.0000835854,0.000008826386,0.00002270806,0.00002562883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8779408,"threshold_uncertainty_score":0.9655294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01383505591741736,"score_gpt":0.2365430042956999,"score_spread":0.2227079483782825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}