{"id":"W2157191168","doi":"10.1128/jvi.00591-13","title":"Both TRIF and IPS-1 Adaptor Proteins Contribute to the Cerebral Innate Immune Response against Herpes Simplex Virus 1 Infection","year":2013,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"TRIF; Herpes simplex virus; Biology; Interferon; Signal transducing adaptor protein; Virology; TLR3; Innate immune system; Immune system; Encephalitis; Immunology; Phosphorylation; Virus; Toll-like receptor; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001307156,0.0002109788,0.0004908559,0.000283444,0.0002518015,0.00004423588,0.0002634094,0.0003030105,0.0004214858],"category_scores_gemma":[0.0008113639,0.0001336812,0.0001568989,0.000130112,0.0002568311,0.0002078385,0.0001363932,0.0005733591,0.000306724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006435805,"about_ca_system_score_gemma":0.0001186381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002677361,"about_ca_topic_score_gemma":0.00005785664,"domain_scores_codex":[0.9970338,0.00163236,0.0006852923,0.0001692831,0.00005126843,0.0004279519],"domain_scores_gemma":[0.9985629,0.0004821712,0.0004449272,0.00024236,0.0002147774,0.00005282112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01327324,0.0001373178,0.0002680277,0.000004929926,0.0003087888,0.00001302145,0.0005629332,0.00001090681,0.9563285,0.00007681972,0.009207477,0.0198081],"study_design_scores_gemma":[0.003974248,0.004629938,0.2086009,0.00004449098,0.00006344305,0.0009668753,0.0002015164,0.00001314763,0.2578377,0.0001025131,0.523343,0.0002222351],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873335,0.00259487,0.0003638642,0.008283982,0.0008354216,0.0004869478,0.00002639606,0.00002035348,0.00005459922],"genre_scores_gemma":[0.9961694,0.0003128154,0.00004513044,0.002011672,0.00009285021,0.00003160188,0.000004915448,0.00001927079,0.001312332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6984907,"threshold_uncertainty_score":0.5451361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01015002181793202,"score_gpt":0.2425605949592957,"score_spread":0.2324105731413637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}