{"id":"W2157215126","doi":"10.4269/ajtmh.2005.73.234","title":"DETECTION OF BENZIMIDAZOLE RESISTANCE–ASSOCIATED MUTATIONS IN THE FILARIAL NEMATODE WUCHERERIA BANCROFTI AND EVIDENCE FOR SELECTION BY ALBENDAZOLE AND IVERMECTIN COMBINATION TREATMENT","year":2005,"lang":"en","type":"article","venue":"American Journal of Tropical Medicine and Hygiene","topic":"Helminth infection and control","field":"Veterinary","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Albendazole; Wuchereria bancrofti; Lymphatic filariasis; Ivermectin; Diethylcarbamazine; Biology; Anthelmintic; Helminthiasis; Microfilaria; Single-nucleotide polymorphism; Filariasis; Nematode; Drug resistance; Veterinary medicine; Helminths; Virology; Immunology; Medicine; Genetics; Genotype; Zoology; Gene; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001847536,0.0002820809,0.0002627927,0.0008620992,0.0002805807,0.0002094417,0.0001750138,0.0004967087,0.001434412],"category_scores_gemma":[0.0008785672,0.0001971593,0.0001454752,0.0004481947,0.0003573034,0.0001259249,0.000127789,0.0002663313,0.0001704398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002376634,"about_ca_system_score_gemma":0.0001022198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00457353,"about_ca_topic_score_gemma":0.007883063,"domain_scores_codex":[0.9997652,0.00004411883,0.00002307911,0.00005495654,0.00005622986,0.00005630263],"domain_scores_gemma":[0.999568,0.0001108112,0.0001792811,0.00002217692,0.00005802,0.00006155881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005841542,0.0001670397,0.7117253,0.00005185694,0.00005203756,0.001936108,0.0002338286,0.00008160413,0.2789327,0.00006084115,0.0001149824,0.006059506],"study_design_scores_gemma":[0.00003755137,0.0003243053,0.9744212,0.00001051047,0.00003652535,0.00524107,0.000151027,0.00035328,0.01907601,0.00002711521,0.0003155399,0.000005862466],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993862,0.0001545515,0.0001044377,0.00002516354,0.000003118936,0.000008168003,0.00007730533,0.000004552803,0.0002364963],"genre_scores_gemma":[0.9993955,0.00008699689,0.0002402446,0.00001859499,0.000002820235,0.000005263267,0.00009662833,0.000001110241,0.000152677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00457353,"threshold_uncertainty_score":0.009093821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04189788405671762,"score_gpt":0.3442287463109101,"score_spread":0.3023308622541925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}