{"id":"W2157215126","doi":"10.4269/ajtmh.2005.73.234","title":"DETECTION OF BENZIMIDAZOLE RESISTANCE–ASSOCIATED MUTATIONS IN THE FILARIAL NEMATODE WUCHERERIA BANCROFTI AND EVIDENCE FOR SELECTION BY ALBENDAZOLE AND IVERMECTIN COMBINATION TREATMENT","year":2005,"lang":"en","type":"article","venue":"American Journal of Tropical Medicine and Hygiene","topic":"Helminth infection and control","field":"Veterinary","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Albendazole; Wuchereria bancrofti; Lymphatic filariasis; Ivermectin; Diethylcarbamazine; Biology; Anthelmintic; Helminthiasis; Microfilaria; Single-nucleotide polymorphism; Filariasis; Nematode; Drug resistance; Veterinary medicine; Helminths; Virology; Immunology; Medicine; Genetics; Genotype; Zoology; Gene; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002551965,0.0000894335,0.0002892366,0.0001051563,0.0000980017,0.00001350597,0.00003517072,0.00003548379,0.00001265066],"category_scores_gemma":[0.0005197777,0.0000600069,0.00003360271,0.000171428,0.0001729232,0.0001379562,0.00000520653,0.0001074006,1.26809e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007609629,"about_ca_system_score_gemma":0.00002672501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002436857,"about_ca_topic_score_gemma":0.0005490694,"domain_scores_codex":[0.9991036,0.0001810629,0.0003723947,0.0001071979,0.0001284232,0.0001073241],"domain_scores_gemma":[0.9988347,0.0006100204,0.0003344746,0.00004518991,0.0001187151,0.0000569433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01099685,0.001253608,0.06503159,0.000153108,0.0004810967,0.0000212029,0.01345296,0.00004142236,0.2866208,0.001346996,0.001364172,0.6192362],"study_design_scores_gemma":[0.01957659,0.03551022,0.914874,0.0007482041,0.0006922482,0.0005116665,0.007274079,0.004797627,0.006502898,0.001084426,0.008103484,0.0003245505],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917065,0.0008716249,0.002421551,0.004712533,0.00006136889,0.0001894032,0.000003656159,0.000005100541,0.00002824432],"genre_scores_gemma":[0.9991665,0.0002956032,0.0001999724,0.0001675557,0.0001299638,0.00001685485,0.000001588775,0.000005492427,0.00001647853],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8498424,"threshold_uncertainty_score":0.244701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04189788405671762,"score_gpt":0.3442287463109101,"score_spread":0.3023308622541925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}