{"id":"W2157220507","doi":"10.1101/gad.1896810","title":"A novel role for 14–3–3σ in regulating epithelial cell polarity","year":2010,"lang":"en","type":"article","venue":"Genes & Development","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research; McGill University Health Centre; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Cell polarity; Polarity (international relations); Ectopic expression; Carcinogenesis; Cell biology; Epithelial polarity; Transgene; Epithelium; Cell culture; Cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002294477,0.000136001,0.0001044152,0.00005058485,0.0001113431,0.00002451947,0.0001651494,0.0001563232,0.00002726177],"category_scores_gemma":[0.00007447851,0.0001420748,0.00005301868,0.00005597697,0.00002285799,0.000004384594,0.00012614,0.0001260675,0.00001543041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002609697,"about_ca_system_score_gemma":0.0002127128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006902515,"about_ca_topic_score_gemma":0.001074115,"domain_scores_codex":[0.9990565,0.00001216541,0.0002468731,0.0003188528,0.00009262569,0.0002729705],"domain_scores_gemma":[0.9995242,0.00001286328,0.00007511747,0.0002379317,0.00009065041,0.00005920589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003818392,0.00008564653,0.002327817,0.00001238869,0.00001333267,3.100194e-7,0.0001490406,0.00001977376,0.9813344,0.00003374762,0.00006297132,0.01592238],"study_design_scores_gemma":[0.0004824185,0.00002909775,0.009419604,0.000007123522,0.000003407172,0.000008323066,0.00005008021,0.00004127443,0.8181017,0.00006720981,0.1716255,0.0001642427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911481,0.0001496206,0.007059594,0.0001156239,0.0004538001,0.0003780242,0.00002159015,0.00001270353,0.0006609272],"genre_scores_gemma":[0.8499475,0.000007986266,0.148278,0.0001172475,0.0002453874,0.0002090893,0.00009784303,0.00002392459,0.001073128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1715625,"threshold_uncertainty_score":0.5793641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009153377197333116,"score_gpt":0.2475624313898588,"score_spread":0.2384090541925257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}