{"id":"W2157220507","doi":"10.1101/gad.1896810","title":"A novel role for 14–3–3σ in regulating epithelial cell polarity","year":2010,"lang":"en","type":"article","venue":"Genes & Development","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research; McGill University Health Centre; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Cell polarity; Polarity (international relations); Ectopic expression; Carcinogenesis; Cell biology; Epithelial polarity; Transgene; Epithelium; Cell culture; Cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119607,0.0002751325,0.000147767,0.0001747377,0.000381477,0.0006158022,0.0003249036,0.0004127836,0.0008700428],"category_scores_gemma":[0.00008870904,0.0001583868,0.0003018271,0.0001321788,0.0004046614,0.0002905063,0.0002848561,0.0004415411,0.0004218639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003404886,"about_ca_system_score_gemma":0.0004186125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007491783,"about_ca_topic_score_gemma":0.00128157,"domain_scores_codex":[0.9999179,0.000006889333,0.000003512806,0.00001976825,0.00002891924,0.0000230381],"domain_scores_gemma":[0.9999335,0.000006637019,0.00001201012,0.00001049895,0.00001020001,0.00002704008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004680144,0.00001134246,0.0008353641,0.00001334752,0.000003725762,0.0002264164,0.00001267326,0.00006800982,0.9952888,0.00112271,0.00004914534,0.002321624],"study_design_scores_gemma":[0.00004150412,0.0003240173,0.03181088,0.00001553548,0.0000333091,0.002261744,0.0001123366,0.003583152,0.9451591,0.002668666,0.01396936,0.00002042372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697914,0.004186287,0.02003162,0.0005479427,0.00009297999,0.00002278027,0.0001545589,0.0002211329,0.004951402],"genre_scores_gemma":[0.9926705,0.0009104856,0.003359243,0.0001071868,0.0000181807,0.000007928517,0.0001287817,0.00001251202,0.002785017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008700428,"threshold_uncertainty_score":0.002910614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009153377197333116,"score_gpt":0.2475624313898588,"score_spread":0.2384090541925257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}