{"id":"W2157223468","doi":"10.1016/j.bbalip.2006.01.003","title":"Biosynthesis of novel carotenoid families based on unnatural carbon backbones: A model for diversification of natural product pathways","year":2006,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Science Foundation","keywords":"Carotenoid; Natural product; Rhodospirillum rubrum; Biochemistry; Biology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001910462,0.0003699411,0.0005018048,0.0001269125,0.00005776485,0.000007140723,0.0003340128,0.0003390456,7.106281e-7],"category_scores_gemma":[0.0000759309,0.0003208614,0.0003213332,0.0001574151,0.0005124468,0.000006372675,0.00009573195,0.000114048,1.208207e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001079883,"about_ca_system_score_gemma":0.0001162641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006420583,"about_ca_topic_score_gemma":0.000004072254,"domain_scores_codex":[0.9983106,0.00008108089,0.0004804317,0.0006695118,0.0001555464,0.0003027931],"domain_scores_gemma":[0.9987031,0.00007652944,0.0004525552,0.0005171304,0.0001949346,0.00005577882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007921231,0.0005393854,0.00003754564,0.0002962388,0.0000905943,2.373752e-7,0.00003522301,0.0002073862,0.9976787,0.0001062062,0.0000419286,0.000174442],"study_design_scores_gemma":[0.0009004073,0.0005320111,0.0002932619,0.00005817015,0.0001433597,0.000001563246,0.00005192582,0.01165378,0.9859463,0.00004146945,0.00003526357,0.0003424942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969212,0.0004265935,0.000521009,0.000210466,0.00008002402,0.0003960989,0.00111865,0.00001369207,0.0003122493],"genre_scores_gemma":[0.9965795,0.0001096731,0.002083451,0.00007677858,0.00009065813,0.00002396513,0.0009739759,0.00002697974,0.00003506878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0117324,"threshold_uncertainty_score":0.9999244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009764757907855911,"score_gpt":0.207714735630365,"score_spread":0.1979499777225091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}