{"id":"W2157401351","doi":"10.1139/o01-032","title":"Class II histone deacetylases: Structure, function, and regulation","year":2001,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":271,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; National Cancer Institute; National Institute for Health and Care Research","keywords":"HDAC4; Histone deacetylase 5; Histone deacetylase 2; HDAC8; Acetylation; Biology; HDAC11; Histone deacetylase; Cell biology; Histone; HDAC1; HDAC10; Corepressor; Histone code; SAP30; Mef2; Transcription factor; Biochemistry; Nucleosome; Enhancer; Repressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001209782,0.0002125692,0.0001680567,0.00004323551,0.000272309,0.00001677982,0.0001062515,0.0004456338,0.0001050376],"category_scores_gemma":[0.0000589778,0.0002080742,0.00004379181,0.00009676829,0.0003758008,0.000004946734,0.0001895269,0.0001507851,0.000004559724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002427837,"about_ca_system_score_gemma":0.00007667989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002128544,"about_ca_topic_score_gemma":0.00001357456,"domain_scores_codex":[0.9987441,0.00005714318,0.0002131957,0.000594506,0.00008112365,0.0003099317],"domain_scores_gemma":[0.9993297,0.00001497999,0.00008109005,0.0003278985,0.00008502195,0.0001612516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001904868,0.00004291724,0.00125809,0.00003796092,0.00002046356,0.000002019764,0.00001286754,0.000002447225,0.9924239,0.00008128701,0.003585646,0.002341903],"study_design_scores_gemma":[0.0006436871,0.0003218614,0.000580964,0.000005744331,0.0000163634,0.00007375628,0.0000343439,0.00002889198,0.798369,0.0001757878,0.199533,0.0002166718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905555,0.005061578,0.0002606081,0.0001604017,0.0001209233,0.0001204308,0.00003999307,0.00002178564,0.003658843],"genre_scores_gemma":[0.989884,0.0006365359,0.0001870979,0.0001615218,0.0003874876,0.00001351112,0.0005342857,0.00001987518,0.008175742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1959473,"threshold_uncertainty_score":0.848502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006674025046067946,"score_gpt":0.247026834925674,"score_spread":0.240352809879606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}