{"id":"W2157421521","doi":"10.1126/science.1176495","title":"A Global Protein Kinase and Phosphatase Interaction Network in Yeast","year":2010,"lang":"en","type":"article","venue":"Science","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":694,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Kinome; Phosphorylation; Phosphatase; Kinase; Protein phosphorylation; Biochemistry; Yeast; Cell biology; Biology; Chemistry; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001341936,0.0002092281,0.0002481489,0.0009358021,0.0003159709,0.0006877515,0.0002211984,0.0001433506,0.001150767],"category_scores_gemma":[0.0004358906,0.0001744956,0.0002010306,0.001303169,0.0003065384,0.0006854408,0.0003380357,0.000169656,0.0001927679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006453607,"about_ca_system_score_gemma":0.0003770609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002444379,"about_ca_topic_score_gemma":0.00318291,"domain_scores_codex":[0.9998695,0.00001909125,0.000006119144,0.00005245552,0.00003680517,0.0000160385],"domain_scores_gemma":[0.9998432,0.00004115147,0.00003427822,0.00001420466,0.00002994182,0.00003708827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009361188,0.0001599924,0.07062683,0.0009734341,0.0005471071,0.00262893,0.0009645793,0.3351818,0.3396691,0.09036875,0.007080631,0.1508627],"study_design_scores_gemma":[0.0001114091,0.0002532861,0.2516455,0.00008006545,0.0005192388,0.002741854,0.000947802,0.4911249,0.0397158,0.1598844,0.05286352,0.0001122408],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9563248,0.002114969,0.03045989,0.0002856782,0.00001095931,0.0000501802,0.002872686,0.0004868266,0.007394056],"genre_scores_gemma":[0.9885744,0.0008341441,0.006701351,0.00002623045,0.000007473248,0.00005205169,0.002459137,0.00002512738,0.001320151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002444379,"threshold_uncertainty_score":0.004860342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007564198984088524,"score_gpt":0.2911190644347816,"score_spread":0.2835548654506931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}