{"id":"W2157466752","doi":"10.1186/1742-4682-7-2","title":"Cancer proliferation and therapy: the Warburg effect and quantum metabolism","year":2010,"lang":"en","type":"article","venue":"Theoretical Biology and Medical Modelling","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Allard Foundation; Alberta Cancer Foundation; Ministry of Advanced Education, Government of Alberta","keywords":"Warburg effect; Cancer cell; Biology; Oxidative phosphorylation; Glycolysis; Anaerobic glycolysis; Cancer; Metabolic pathway; Systems biology; Bioinformatics; Cell biology; Computational biology; Metabolism; Genetics; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008258257,0.0001630365,0.0002225158,0.00001985829,0.0001725563,0.0000202981,0.00009940959,0.0003902045,0.00005501593],"category_scores_gemma":[0.0001833668,0.00009126514,0.00003649628,0.00003155604,0.001623762,0.000004020586,0.00008917371,0.000367887,6.415992e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":9.511152e-7,"about_ca_system_score_gemma":0.00005178274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002173586,"about_ca_topic_score_gemma":0.000009429325,"domain_scores_codex":[0.9989826,0.0001689103,0.0001570831,0.0003448712,0.0000952063,0.0002513462],"domain_scores_gemma":[0.9994338,0.000132007,0.0000334073,0.0001617067,0.00003354047,0.0002055368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006368912,0.0000392765,0.001195231,0.00002544794,0.0001159578,8.586674e-7,0.0002207059,0.0000132538,0.2270014,0.5700879,0.00009747435,0.2005656],"study_design_scores_gemma":[0.008503157,0.001595722,0.002187792,0.0001018179,0.0004988453,0.0003919249,0.000101247,0.1376023,0.1667122,0.2949778,0.3858569,0.001470161],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620233,0.02696403,0.008140132,0.001807585,0.000697974,0.0002297569,0.000007990939,0.00001220337,0.0001169965],"genre_scores_gemma":[0.9581019,0.03892215,0.0001275625,0.001117785,0.001623033,0.00005770478,0.00001480378,0.00001244986,0.00002262794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3857595,"threshold_uncertainty_score":0.5982818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006909479874947421,"score_gpt":0.2715668344048487,"score_spread":0.2646573545299012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}