{"id":"W2157597981","doi":"10.1081/bio-120002725","title":"CROSS-LINKED POLYHEMOGLOBIN-SUPEROXIDE DISMUTASE-CATALASE SUPPLIES OXYGEN WITHOUT CAUSING BLOOD BRAIN BARRIER DISRUPTION OR BRAIN EDEMA IN A RAT MODEL OF TRANSIENT GLOBAL BRAIN ISCHEMIA-REPERFUSION","year":2002,"lang":"en","type":"article","venue":"Artificial Cells Blood Substitutes and Biotechnology","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Ischemia; Superoxide dismutase; Catalase; Reperfusion injury; Hemoglobin; Edema; Anesthesia; Blood substitute; Brain ischemia; Medicine; Reactive oxygen species; Oxygen; Chemistry; Pharmacology; Internal medicine; Oxidative stress; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002347852,0.0005412499,0.000343514,0.0003065749,0.00009027187,0.0001607155,0.000209369,0.000237188,0.0009703836],"category_scores_gemma":[0.000170437,0.0001361438,0.0001645128,0.0001953807,0.0002413978,0.0002201628,0.0001204578,0.0004140196,0.0001283846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001224288,"about_ca_system_score_gemma":0.0002138867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002550854,"about_ca_topic_score_gemma":0.000387357,"domain_scores_codex":[0.9998789,0.00002705553,0.00001519625,0.00001915378,0.00003305102,0.00002677855],"domain_scores_gemma":[0.9998581,0.00001597713,0.00004990275,0.00001863552,0.00002169744,0.00003557085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004178341,0.000121676,0.0001406375,0.00005855156,0.00001232683,0.00004348287,0.00001431007,0.00005644963,0.9970099,0.00008505637,0.00002895979,0.002010802],"study_design_scores_gemma":[0.00003867589,0.001545265,0.0006225701,0.000005141449,0.00004198897,0.0001428815,0.000009190824,0.0003765603,0.9966444,0.00003527173,0.0005356514,0.000002392529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959773,0.0008173112,0.002698587,0.00005022656,0.00003655699,0.00002158459,0.00005916996,0.00005688323,0.00028236],"genre_scores_gemma":[0.9919767,0.001321737,0.004594966,0.00003961948,0.00002250436,0.000040343,0.0003018462,0.00002024092,0.001681983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009703836,"threshold_uncertainty_score":0.003246307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01380130774171961,"score_gpt":0.2440742484476296,"score_spread":0.23027294070591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}