{"id":"W2157597981","doi":"10.1081/bio-120002725","title":"CROSS-LINKED POLYHEMOGLOBIN-SUPEROXIDE DISMUTASE-CATALASE SUPPLIES OXYGEN WITHOUT CAUSING BLOOD BRAIN BARRIER DISRUPTION OR BRAIN EDEMA IN A RAT MODEL OF TRANSIENT GLOBAL BRAIN ISCHEMIA-REPERFUSION","year":2002,"lang":"en","type":"article","venue":"Artificial Cells Blood Substitutes and Biotechnology","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Ischemia; Superoxide dismutase; Catalase; Reperfusion injury; Hemoglobin; Edema; Anesthesia; Blood substitute; Brain ischemia; Medicine; Reactive oxygen species; Oxygen; Chemistry; Pharmacology; Internal medicine; Oxidative stress; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002706409,0.0004245375,0.0004746616,0.000144282,0.0002116522,0.00006084471,0.000213659,0.001007722,0.00005210675],"category_scores_gemma":[0.0002083249,0.0003700166,0.0001439314,0.0003788951,0.000649398,0.00003725099,0.0001683931,0.0002671184,0.000004368505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002799398,"about_ca_system_score_gemma":0.00008412738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001585864,"about_ca_topic_score_gemma":0.00119433,"domain_scores_codex":[0.9975555,0.00006700734,0.0006924187,0.0008794775,0.0002098782,0.0005957068],"domain_scores_gemma":[0.9990603,0.00004429677,0.0001650146,0.0005136756,0.00006869837,0.0001480691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004237401,0.0003216581,0.001652564,0.00006545707,0.00006626558,0.00004526059,0.0001907287,0.0005045518,0.9923686,0.0005171299,0.0003475035,0.003496578],"study_design_scores_gemma":[0.001769012,0.0004648169,0.00008946616,0.00004075837,0.0001067624,0.0001786189,0.0001714515,0.003368952,0.9918747,0.0003664668,0.001130647,0.0004383471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937121,0.0008552924,0.001524422,0.002886601,0.0002006641,0.0004674662,0.0002376078,0.00006163193,0.00005425206],"genre_scores_gemma":[0.9973953,0.0002650712,0.001094765,0.0005922973,0.0001193513,0.00002351031,0.000210421,0.00003122488,0.0002680974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003683199,"threshold_uncertainty_score":0.9998752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01380130774171961,"score_gpt":0.2440742484476296,"score_spread":0.23027294070591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}