{"id":"W2157640230","doi":"10.1016/j.celrep.2014.06.048","title":"Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a","year":2014,"lang":"en","type":"article","venue":"Cell Reports","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"DNA methylation; Methylation; Methyltransferase; Biology; Epigenetics; RNA-Directed DNA Methylation; Epigenomics; Phosphorylation; DNA methyltransferase; CpG site; Epigenetics of physical exercise; DNA; Cell biology; Molecular biology; Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004639325,0.0001033637,0.0001527237,0.00004672677,0.0000249147,0.000005225588,0.00004685314,0.0001611182,0.00003202201],"category_scores_gemma":[0.0001737874,0.0001065294,0.00006989529,0.00008502921,0.00003180441,0.000004978066,0.00002690253,0.00003575974,0.000001118787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008769362,"about_ca_system_score_gemma":0.00002793699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002928838,"about_ca_topic_score_gemma":0.000006956036,"domain_scores_codex":[0.998876,0.00006987618,0.0005088205,0.0002467935,0.0001932996,0.000105226],"domain_scores_gemma":[0.9987448,0.00002633996,0.0006403586,0.000354452,0.000189959,0.00004405234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001443577,0.00004487674,0.03692503,0.00003673815,0.000009635141,2.4608e-7,0.00003227133,0.0003384655,0.9598373,0.000008959425,0.0002240969,0.002527971],"study_design_scores_gemma":[0.0001703446,0.0001420532,0.0608556,0.00001032268,0.00001834196,8.230689e-7,0.000008014873,0.0004464568,0.9323913,0.0002772308,0.005581745,0.00009778224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660375,0.0006050533,0.03087227,0.0000120982,0.0001448151,0.0001466067,0.000009861488,0.000006968879,0.002164848],"genre_scores_gemma":[0.9979916,0.0001251314,0.0004105271,0.000009300973,0.00005865073,0.000005490394,0.001020701,0.00001745238,0.0003611257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03195414,"threshold_uncertainty_score":0.4344144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005891427107294215,"score_gpt":0.2198900667575756,"score_spread":0.2139986396502814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}