{"id":"W2157668374","doi":"10.2174/138161211798220963","title":"(Pro)renin Receptor as a New Drug Target","year":2011,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Renin–angiotensin system; Receptor; Medicine; Pharmacology; Drug; Pathogenesis; Intracellular; Endocrinology; Internal medicine; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000655769,0.0008461955,0.001223388,0.0001245604,0.0001193749,0.00008312896,0.0008337265,0.0005208276,0.004614979],"category_scores_gemma":[0.0002369702,0.0007056786,0.0008573206,0.0002280396,0.00008962167,0.000008020234,0.0002898673,0.000817909,0.001578483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005660566,"about_ca_system_score_gemma":0.001188399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004199177,"about_ca_topic_score_gemma":1.215724e-7,"domain_scores_codex":[0.9963651,0.0006487455,0.0007974665,0.001126665,0.0002933591,0.0007686936],"domain_scores_gemma":[0.9979584,0.00006806089,0.0003058787,0.0005688512,0.00008674117,0.001012072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006102826,0.0001338547,1.944443e-7,0.001557394,0.0001942335,0.000003773208,0.00002400186,8.474017e-7,0.001422677,0.0005174864,0.104709,0.8913755],"study_design_scores_gemma":[0.0004014921,0.0001848086,1.322532e-8,0.001865397,0.0005128285,0.00002637635,0.000002701324,0.00001507047,0.02187901,0.0003452714,0.9739486,0.0008184531],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000001888047,0.953675,0.04198881,0.00001975843,0.00246343,0.001275079,0.00004796587,0.00005809981,0.0004699502],"genre_scores_gemma":[0.000004656329,0.988335,0.005726022,0.0001155318,0.001701784,0.0001885956,0.0005796992,0.0001565768,0.0031922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8905571,"threshold_uncertainty_score":0.9995394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1808231314618856,"score_gpt":0.4090932349840491,"score_spread":0.2282701035221636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}