{"id":"W2157693527","doi":"10.1042/bj20140459","title":"Switching on ubiquitylation by phosphorylating a ubiquitous activator","year":2014,"lang":"en","type":"letter","venue":"Biochemical Journal","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Phosphorylation; Activator (genetics); Ubiquitin; Cell biology; Chemistry; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005482657,0.00033282,0.0002916783,0.0001405578,0.0004481646,0.0007077239,0.000440621,0.003869183,0.002163613],"category_scores_gemma":[0.001986159,0.0001618418,0.0003668726,0.0001442784,0.0008222348,0.0005656713,0.0004021682,0.002478086,0.002020451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001161847,"about_ca_system_score_gemma":0.0002029049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001863229,"about_ca_topic_score_gemma":0.0002989219,"domain_scores_codex":[0.9994693,0.0001458341,0.00004730343,0.00007526106,0.0001595782,0.0001026985],"domain_scores_gemma":[0.9994936,0.0002625465,0.00008223169,0.00005459407,0.00004662571,0.00006043266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002939872,0.0004686973,0.009352679,0.0006143964,0.0001111901,0.129699,0.0006514134,0.0007883546,0.195258,0.03784255,0.4006325,0.2216414],"study_design_scores_gemma":[0.0004208107,0.0007091272,0.007627858,0.0001344341,0.00006782931,0.0742826,0.0004238677,0.002598058,0.06036475,0.01762367,0.8356702,0.00007679678],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1625057,0.03245117,0.00810532,0.6844763,0.02754386,0.0001971883,0.0002741095,0.0009328186,0.08351357],"genre_scores_gemma":[0.700449,0.01421486,0.003220789,0.2105651,0.02385085,0.0002087946,0.0001470011,0.00008113688,0.04726245],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003869183,"threshold_uncertainty_score":0.008429825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01472238331719954,"score_gpt":0.2479278448531195,"score_spread":0.23320546153592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}