{"id":"W2157821338","doi":"10.1093/molehr/gar004","title":"Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility","year":2011,"lang":"en","type":"review","venue":"Molecular Human Reproduction","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kinexus Bioinformatics Corporation (Canada)","funders":"","keywords":"Biology; Protein phosphatase 1; Sperm; Phosphatase; Motility; Phosphorylation; Cell biology; Sperm motility; Kinase; Protein kinase A; Gene isoform; Male infertility; Serine; Infertility; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005783321,0.0005823431,0.0008267934,0.000115171,0.0002664256,0.00006738478,0.00030792,0.0004223568,0.00006198542],"category_scores_gemma":[0.0003383508,0.0005808418,0.0004834429,0.0001072068,0.000230162,0.0000108716,0.000341184,0.0003177507,0.000009816888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007229954,"about_ca_system_score_gemma":0.0000951168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000135312,"about_ca_topic_score_gemma":0.00002314333,"domain_scores_codex":[0.9965973,0.0001890494,0.0007255597,0.001912804,0.0001691721,0.0004060996],"domain_scores_gemma":[0.9971871,0.000008052851,0.000471024,0.001938358,0.0002610175,0.0001344855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002908708,0.002160371,0.00005458047,0.03017874,0.001879329,0.00002247948,0.0001222745,0.00004403379,0.4071351,0.002600895,0.002107396,0.5534039],"study_design_scores_gemma":[0.000345276,0.000259131,0.00008296738,0.0005411353,0.0003331772,0.0001212866,0.000004613426,0.000008337655,0.1044977,0.0003342866,0.8929698,0.0005023452],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0110243,0.9769672,0.005503592,0.0000386959,0.0003222705,0.005547283,0.0004128345,0.00005313714,0.000130688],"genre_scores_gemma":[0.04871474,0.8956609,0.01587096,0.00008832395,0.003291509,0.01069927,0.01458066,0.0007369666,0.01035666],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8908623,"threshold_uncertainty_score":0.9996643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06070465988408612,"score_gpt":0.3370889586767087,"score_spread":0.2763842987926226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}