{"id":"W2157848799","doi":"10.1016/j.jmb.2006.01.080","title":"Binding Properties of Pyochelin and Structurally Related Molecules to FptA of Pseudomonas aeruginosa","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation","keywords":"Siderophore; Chemistry; Stereochemistry; Denticity; Docking (animal); Burkholderia; Binding site; Molecule; Chelation; Carboxylate; Biochemistry; Bacteria; Crystallography; Biology; Organic chemistry; Crystal structure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002124925,0.0002361527,0.0001827827,0.0002265962,0.0002848515,0.0002514377,0.000293275,0.0003551414,0.001669839],"category_scores_gemma":[0.0007277421,0.0001648009,0.0001928903,0.0002155512,0.0002193389,0.0002565557,0.0002241677,0.0004455581,0.0003018824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003033972,"about_ca_system_score_gemma":0.0001749674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002528596,"about_ca_topic_score_gemma":0.001171941,"domain_scores_codex":[0.9998255,0.00004531359,0.000007037525,0.00002682438,0.00004796912,0.00004745396],"domain_scores_gemma":[0.9996369,0.0002086374,0.00003101222,0.00001897378,0.00004273699,0.00006175539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003281287,0.00002068455,0.0004567499,0.00002396059,0.000005720342,0.00003712366,0.00003893057,0.00009936019,0.9983418,0.00004590294,0.00001752879,0.0005841054],"study_design_scores_gemma":[0.00002785614,0.0006001524,0.02869593,0.000007967404,0.00001842568,0.0002124792,0.0002344647,0.002211127,0.966815,0.0001065417,0.001051496,0.00001857813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989518,0.0002644,0.0002712378,0.00002627249,0.000003998109,0.000003952754,0.00005030954,0.000003428123,0.0004245242],"genre_scores_gemma":[0.9984403,0.0001088684,0.0002617619,0.00002937254,0.000005725201,0.000009295039,0.0002236921,0.000004408876,0.0009165247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002528596,"threshold_uncertainty_score":0.005586207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006468592627824729,"score_gpt":0.2232933153541507,"score_spread":0.2168247227263259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}