{"id":"W2157930949","doi":"10.1038/nature05571","title":"Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis","year":2007,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1763,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Notch signaling pathway; Sprouting angiogenesis; Cell biology; Angiogenesis; Biology; Sprouting; Endothelial stem cell; Signalling; Chemistry; Neovascularization; Signal transduction; Cancer research; Genetics; In vitro; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003080692,0.0002657337,0.0003351389,0.0004662335,0.0004330848,0.0009674476,0.0005149142,0.0004540215,0.001195116],"category_scores_gemma":[0.0003313143,0.0003821401,0.0002762279,0.0001864626,0.0003121155,0.000568986,0.0007622187,0.00122162,0.0007560059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001579858,"about_ca_system_score_gemma":0.0003776356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296583,"about_ca_topic_score_gemma":0.002341464,"domain_scores_codex":[0.9996252,0.00006237622,0.00002393939,0.00005554447,0.00009156599,0.0001414402],"domain_scores_gemma":[0.9996234,0.00004112156,0.00009081332,0.00002823781,0.00007011543,0.000146373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203288,0.00001098567,0.0006622729,0.00003346727,0.000004653665,0.0001414357,0.00003270148,0.0001648206,0.9960192,0.0007300883,0.0001855121,0.00179447],"study_design_scores_gemma":[0.00003066121,0.00008049666,0.02732795,0.00001643582,0.00001695237,0.0002713355,0.0001578604,0.002751452,0.9631693,0.0004617862,0.005705416,0.00001041877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800336,0.004432026,0.007711082,0.0003483825,0.00006669608,0.00003676899,0.000424499,0.0001913916,0.006755575],"genre_scores_gemma":[0.9899832,0.0007846096,0.002095657,0.0001019694,0.00002538874,0.00003221989,0.0003912769,0.00006192338,0.006523742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001579858,"threshold_uncertainty_score":0.01146269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004404798550353197,"score_gpt":0.2297969362330513,"score_spread":0.2253921376826981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}