{"id":"W2157987233","doi":"10.1186/1744-8069-6-50","title":"Combining Ketamine with Astrocytic Inhibitor as a Potential Analgesic Strategy for Neuropathic Pain. Ketamine, Astrocytic Inhibitor and Pain","year":2010,"lang":"en","type":"article","venue":"Molecular Pain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; National Natural Science Foundation of China","keywords":"Neuropathic pain; Ketamine; NMDA receptor; Medicine; Pharmacology; Analgesic; Antagonist; Anesthesia; Allodynia; Glutamate receptor; Astrocyte; Spinal nerve; Hyperalgesia; Nociception; Spinal cord; Receptor; Central nervous system; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009858385,0.0003499031,0.0003741719,0.0002184423,0.0001369631,0.0001906679,0.0002664345,0.0002023091,0.0009242055],"category_scores_gemma":[0.00006055824,0.00008487868,0.0003112449,0.0001929411,0.0001569743,0.0002437977,0.0001889619,0.0004940698,0.000225948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001369197,"about_ca_system_score_gemma":0.0003084145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003396182,"about_ca_topic_score_gemma":0.001405858,"domain_scores_codex":[0.999934,0.00001116264,0.000009064202,0.00001080223,0.00001624486,0.0000187911],"domain_scores_gemma":[0.9999715,0.00000200453,0.00001005795,0.000002624818,0.000004650429,0.000009190357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002028627,0.001172565,0.0007615117,0.001145264,0.00008557286,0.0004942153,0.00003679531,0.0002152192,0.9508365,0.000531535,0.0004644463,0.04222776],"study_design_scores_gemma":[0.001212957,0.02976743,0.01583868,0.0001753836,0.0005531797,0.005351026,0.0001133788,0.001952605,0.9196489,0.0004687054,0.02487998,0.00003767132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9252159,0.06098016,0.00640431,0.0006296244,0.0003423953,0.0003711188,0.0003494116,0.0001546491,0.005552422],"genre_scores_gemma":[0.9508728,0.0399146,0.005926281,0.0002769883,0.0001202284,0.0002140988,0.0003763217,0.00001151143,0.002286952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009242055,"threshold_uncertainty_score":0.003091753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007378371646373614,"score_gpt":0.231195225428815,"score_spread":0.2238168537824414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}