{"id":"W2157999348","doi":"10.1080/10408440591007395","title":"Mode of Action: Impaired Fetal Leydig Cell Function—Effects on Male Reproductive Development Produced by Certain Phthalate Esters","year":2005,"lang":"en","type":"review","venue":"Critical Reviews in Toxicology","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Health Canada; U.S. Environmental Protection Agency","keywords":"Phthalate; Mode of action; Endocrinology; Leydig cell; Fetus; Biology; Semen quality; Internal medicine; Hypospadias; Physiology; Pregnancy; Hormone; Sperm; Medicine; Toxicology; Chemistry; Genetics; Luteinizing hormone","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005967143,0.0007248095,0.0004222176,0.0005893838,0.0001462411,0.0004513321,0.0006206057,0.0007752813,0.002606538],"category_scores_gemma":[0.0002652422,0.0001279494,0.0003304938,0.0002450347,0.0006729894,0.0003782029,0.000336921,0.0005376965,0.0007401969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005574315,"about_ca_system_score_gemma":0.0004153154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008121437,"about_ca_topic_score_gemma":0.000889974,"domain_scores_codex":[0.999667,0.000122822,0.00002218216,0.00006475377,0.00009517361,0.0000280434],"domain_scores_gemma":[0.9997891,0.00007123967,0.0000605999,0.0000235566,0.00004422288,0.00001134623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00129622,0.0003098586,0.009550832,0.009941581,0.0003232426,0.005041325,0.0003274539,0.00298705,0.4780163,0.03878609,0.01308644,0.4403337],"study_design_scores_gemma":[0.0001821481,0.004117491,0.03228204,0.0008885646,0.0003816071,0.02589857,0.000323578,0.001333299,0.5466074,0.01133124,0.3765693,0.00008477589],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1471938,0.7394447,0.04901692,0.006963472,0.001067663,0.0003475817,0.001269085,0.000601294,0.05409558],"genre_scores_gemma":[0.5712271,0.3942593,0.006659238,0.001599674,0.0005641831,0.0001521225,0.000313379,0.00003523297,0.02518973],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002606538,"threshold_uncertainty_score":0.008719742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04930324193233613,"score_gpt":0.4235161581649582,"score_spread":0.3742129162326221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}