{"id":"W2158026299","doi":"10.1371/journal.pone.0044055","title":"Involvement of AMPA Receptor GluR2 and GluR3 Trafficking in Trigeminal Spinal Subnucleus Caudalis and C1/C2 Neurons in Acute-Facial Inflammatory Pain","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; School of Dentistry, Nihon University; Nihon University","keywords":"AMPA receptor; Spinal trigeminal nucleus; Chemistry; Nociception; Molecular biology; Receptor; Microglia; Internal medicine; Inflammation; Endocrinology; Medicine; Biology; Glutamate receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009361369,0.0004330759,0.0002791926,0.000332576,0.000271682,0.0003165872,0.0003510831,0.0004905346,0.001087083],"category_scores_gemma":[0.0001292698,0.0001623479,0.000267801,0.0001466954,0.0003564916,0.0002991026,0.0002024218,0.0005704288,0.0001842257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006739711,"about_ca_system_score_gemma":0.000383222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004087963,"about_ca_topic_score_gemma":0.003962714,"domain_scores_codex":[0.999823,0.000009054556,0.00001167621,0.00003715106,0.00005453623,0.00006446194],"domain_scores_gemma":[0.9998643,0.000006211279,0.00005142174,0.000009580756,0.00002301173,0.00004553138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001658898,0.00001349462,0.000516887,0.00002211658,0.00000506903,0.000106271,0.00001686451,0.00004681936,0.9984876,0.00006773051,0.0000160784,0.0005350599],"study_design_scores_gemma":[0.00007418845,0.0004636664,0.1567308,0.00002815669,0.00005991845,0.001851576,0.0002621277,0.002281702,0.8371636,0.0001978617,0.0008642907,0.00002225505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99803,0.0006205007,0.0006257265,0.00002971835,0.000004561021,0.000009555951,0.0001247825,0.00001287092,0.0005423103],"genre_scores_gemma":[0.9974834,0.0003419886,0.0007045727,0.00003212944,0.000003266884,0.0000354398,0.0002106726,0.00001074124,0.001177761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004087963,"threshold_uncertainty_score":0.008128345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0378315565363168,"score_gpt":0.2509076489189811,"score_spread":0.2130760923826643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}